NDLI: Evaluation of erythrocyte flow at a bearing gap in a hydrodynamically levitated centrifugal blood pump

Content Provider	IEEE Xplore Digital Library
Author	Murashige, T. Kosaka, R. Sakota, D. Nishida, M. Kawaguchi, Y. Yamane, T. Maruyama, O.
Copyright Year	2015
Description	Author affiliation: Tokyo Univ. of Sci., Chiba, Japan (Kawaguchi, Y.) \|\| Grad. Sch. of Sci. & Technol., Tokyo Univ. of Sci., Chiba, Japan (Murashige, T.) \|\| Grad. Sch. of Eng., Kobe Univ., Kobe, Japan (Yamane, T.) \|\| Nat. Inst. of Adv. Ind. Sci. & Technol., Tsukuba, Japan (Kosaka, R.; Sakota, D.; Nishida, M.; Maruyama, O.)
Abstract	We have developed a hydrodynamically levitated centrifugal blood pump for extracorporeal circulatory support. In the blood pump, a spiral groove bearing was adopted for a thrust bearing. In the spiral groove bearing, separation of erythrocytes and plasma by plasma skimming has been postulated to occur. However, it is not clarified that plasma skimming occurs in a spiral groove bearing. The purpose of this study is to verify whether plasma skimming occurs in the spiral groove bearing of a hydrodynamically levitated centrifugal blood pump. For evaluation of plasma skimming in the spiral groove bearing, an impeller levitation performance test using a laser focus displacement meter and a microscopic visualization test of erythrocyte flow using a high-speed microscope were conducted. Bovine blood diluted with autologous plasma to adjust hematocrit to 1.0% was used as a working fluid. Hematocrit on the ridge region in the spiral groove bearing was estimated using image analysis. As a result, hematocrits on the ridge region with gaps of 45 μm, 31 μm, and 25 μm were calculated as 1.0%, 0.6%, and 0.3%, respectively. Maximum skimming efficiency in this study was calculated as 70% with a gap of 25 μm. We confirmed that separation of erythrocyte and plasma occurred in the spiral groove bearing with decrease in bearing gap in a hydrodynamically levitated centrifugal blood pump.
Starting Page	270
Ending Page	273
File Size	959126
Page Count	4
File Format	PDF
ISSN	1557170X
e-ISBN	9781424492718
DOI	10.1109/EMBC.2015.7318352
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2015-08-25
Publisher Place	Italy
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Blood Plasmas Impellers Hydrodynamics Levitation Microscopy Visualization
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

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