NDLI: Neural Interfaces for Intracortical Recording: Requirements, Fabrication Methods, and Characteristics

Content Provider	frontiers
Author	Szostak, Katarzyna M. Grand, Laszlo Constandinou, Timothy G.
Abstract	Implantable neural interfaces for central nervous system research have been designed with wire, polymer, or micromachining technologies over the past 70 years. Research on biocompatible materials, ideal probe shapes, and insertion methods has resulted in building more and more capable neural interfaces. Although the trend is promising, the long-term reliability of such devices has not yet met the required criteria for chronic human application. The performance of neural interfaces in chronic settings often degrades due to foreign body response to the implant that is initiated by the surgical procedure, and related to the probe structure, and material properties used in fabricating the neural interface. In this review, we identify the key requirements for neural interfaces for intracortical recording, describe the three different types of probes—microwire, micromachined, and polymer-based probes; their materials, fabrication methods, and discuss their characteristics and related challenges.
ISSN	1662453X
DOI	10.3389/fnins.2017.00665
Volume Number	11
Journal	Frontiers in Neuroscience
Language	English
Publisher Date	2017-12-07
Access Restriction	Open
Subject Keyword	Microfabrication techniques Intracortical Microsystems Implantable microtechnologies Neural interface Fabrication Neural probe Microelectrodes
Content Type	Text
Resource Type	Article
Subject	Neuroscience

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Neural Interfaces for Intracortical Recording: Requirements, Fabrication Methods, and Characteristics