NDLI: An ingestible, NIR-fluorometric, cancer-screening capsule

Content Provider	IEEE Xplore Digital Library
Author	Demosthenous, P. Georgiou, J.
Copyright Year	2015
Description	Author affiliation: Dept. of Electr. & Comput. Eng., Univ. of Cyprus, Nicosia, Cyprus (Demosthenous, P.; Georgiou, J.)
Abstract	Asymptomatic, early-stage, cancer detection is a problem in the small intestine, that is largely inaccessible. This paper presents a cost-effective screening capsule prototype, which is able to detect infrared (IR) fluorescence emitted by indocyanine green (ICG) fluorophore dye. The presented mixed-signal system has a small size, consumes little power and works as a high-sensitivity fluorometer that records fluorescence levels throughout the small intestine, rather than collecting images that need labour intensive video analysis. Ex-vivo experiments, on ICG-impregnated swine intestine, have shown that the prototype system is able to detect low concentrations of ICG in the nanomolar and micromolar region, which is required to detect early cancer in the small intestine.
Starting Page	2143
Ending Page	2146
File Size	5758376
Page Count	4
File Format	PDF
ISSN	1557170X
e-ISBN	9781424492718
DOI	10.1109/EMBC.2015.7318813
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2015-08-25
Publisher Place	Italy
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Intestines Cancer Endoscopes Yttrium Prototypes Imaging Photodiodes
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

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