NDLI: Sparse dictionary learning for fMRI analysis using autocorrelation maximization

Content Provider	IEEE Xplore Digital Library
Author	Khalid, M.U. Shah, A. Seghouane, A.-K.
Copyright Year	2015
Description	Author affiliation: Dept. of Electr. & Electron. Eng., Melbourne Univ., Melbourne, VIC, Australia (Shah, A.; Seghouane, A.-K.) \|\| Coll. of Eng. & Comput. Sci., Australian Nat. Univ., Canberra, ACT, Australia (Khalid, M.U.)
Abstract	In this paper, the effect of temporal autocorrelations in functional magnetic resonance imaging (fMRI) data on sparse dictionary learning (SDL) is addressed. For sparse general linear model (sGLM), the fMRI time-series is modeled as a linear mixture of several signals such as neural dynamics, structured noise, random noise and unexplained signal variations on the basis of spatial sparseness. These signals are considered as underlying sources and SDL is used to estimate them. However, the sparse GLM model does not take into account the autocorrelations in fMRI data. To address this shortcoming, a new model is proposed to incorporate the prior knowledge about lag-1 autocorrelation into dictionary update stage. This helps improve the sensitivity and specificity of the fMRI data during statistical analysis. Using a simulation study, the effect of the proposed dictionary update on sGLM is compared to conventional sGLM by utilizing various detrending techniques. Furthermore, the proposed update is validated in an sGLM framework for real fMRI datasets, which shows its better capability to estimate neural dynamics in presence of spatiotemporal dependencies.
Starting Page	4286
Ending Page	4289
File Size	655005
Page Count	4
File Format	PDF
ISSN	1557170X
e-ISBN	9781424492718
DOI	10.1109/EMBC.2015.7319342
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2015-08-25
Publisher Place	Italy
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Dictionaries Correlation Signal processing Principal component analysis Indexes Spatiotemporal phenomena statistical analysis fMRI sparsity SDL sGLM autocorrelations
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

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