NDLI: Malaria in the Renaissance: remedies from European herbals from the 16th and 17th century.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Adams, Michael Alther, Wandana Kessler, Michael Kluge, Martin Hamburger, Matthias
Spatial Coverage	Europe
Description	Country affiliation: Switzerland Author Affiliation: Adams M ( Institute of Pharmaceutical Biology, University of Basel, Klingelbergstrasse 50, CH-4056 Basel, Switzerland. michael.adams@unibas.ch)
Abstract	BACKGROUND: From antiquity up into the 20th century tertian and quartan malaria which are caused by the parasites Plasmodium vivax and Plasmodium malariae were widespread in Central Europe. Hundreds of different remedies against malaria can be found in herbals from the Renaissance. AIM OF THE STUDY: To document and discuss from a modern pharmacological viewpoint the old remedies described in eight 16th and 17th century herbals written in German. MATERIALS AND METHODS: Eight of the most important herbals of the 16th and 17th century including Bock (1577), Fuchs (1543), Matthiolus (1590), Lonicerus (1560), Brunfels (1532), Zwinger (1696), and Tabernaemontanus (1591 and 1678) were searched for terms related to malaria, and documented plants and recipes described for its treatment. Additionally the overlapping of these remedies with those in De Materia Medica by the Greek physician Dioscorides was studied. RESULTS: Three hundred and fourteen taxa were identified in the herbals for this indication. Recent pharmacological data was found for just 5% of them. The influence of De Materia Medica was shown to be negligible with only 3.5% of the remedies in common. CONCLUSIONS: European Renaissance herbals may be a valuable source of information for the selection of plants for focussed antiplasmodial screening programmes, but have received only little scientific attention. Antimalarial remedies from these herbals must be viewed as independent sources of knowledge separate from Dioscorides' De Materia Medica.
File Format	HTM / HTML
ISSN	03788741
Issue Number	2
Volume Number	133
e-ISSN	18727573
Journal	Journal of Ethnopharmacology
Language	English
Publisher	Elsevier
Publisher Date	2011-01-27
Publisher Place	Ireland
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Ethnopharmacology Malaria Drug Therapy Phytotherapy Antimalarials History Therapeutic Use Ethnopharmacology Europe History, 16th Century History, 17th Century Humans Plant Preparations Plants, Medicinal Historical Article Journal Article Review
Content Type	Text
Resource Type	Article
Subject	Drug Discovery Pharmacology

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