NDLI: Reactant minimization during sample preparation on digital microfluidic biochips using skewed mixing trees

Content Provider	IEEE Xplore Digital Library
Author	Juinn-Dar Huang Chia-Hung Liu Ting-Wei Chiang
Copyright Year	2012
Description	Author affiliation: EECS Undergraduate Honors Program, National Chiao Tung University, 1001 University Road, Hsinchu 300, Taiwan (Ting-Wei Chiang) \|\| Dept. of Electronics Engineering, National Chiao Tung University, 1001 University Road, Hsinchu 300, Taiwan (Juinn-Dar Huang; Chia-Hung Liu)
Abstract	Sample preparation is an indispensable process to biochemical reactions. Original reactants are usually diluted to the solutions with desirable concentrations. Since the reactants, like infant's blood, DNA evidence collected from a crime scene, or costly reagents, are extremely valuable, the usage of reactant must be minimized in the sample preparation process. In this paper, we propose the first reactant minimization approach, REMIA, during sample preparation on digital microfluidic biochips (DMFBs). Given a target concentration, REMIA constructs a skewed mixing tree to guide the sample preparation process for reactant minimization. Experimental results demonstrate that REMIA can save about 31%∼52% of reactant usage on average compared with three existing sample preparation methods. Besides, REMIA can be extended to tackle the sample preparation problem with multiple target concentrations, and the extended version also successfully decreases the reactant usage further.
Starting Page	377
Ending Page	383
File Size	3374255
Page Count	7
File Format	PDF
ISBN	9781450315739
ISSN	10923152
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2012-11-05
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Association for Computing Machinery, Inc. (ACM)
Subject Keyword	Minimization Vegetation Educational institutions Blood Algorithm design and analysis Physiology Mixers mixing tree Biochip digital microfluidic biochip (DMFB) dilution sample preparation reactant minimization
Content Type	Text
Resource Type	Article
Subject	Computer Graphics and Computer-Aided Design Computer Science Applications Software

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Reactant minimization during sample preparation on digital microfluidic biochips using skewed mixing trees

Reactant Minimization in Sample Preparation on Digital Microfluidic Biochips

Reactant and Waste Minimization in Multitarget Sample Preparation on Digital Microfluidic Biochips

Sample preparation for many-reactant bioassay on DMFBs using common dilution operation sharing

Volume-oriented sample preparation for reactant minimization on flow-based microfluidic biochips with multi-segment mixers

Reactant Minimization for Sample Preparation on Microfluidic Biochips With Various Mixing Models

Sample preparation for many-reactant bioassay on DMFBs using common dilution operation sharing

Graph-based optimal reactant minimization for sample preparation on digital microfluidic biochips

Sample preparation for droplet-based microfluidics

Reactant minimization during sample preparation on digital microfluidic biochips using skewed mixing trees

Similar Documents

Reactant minimization during sample preparation on digital microfluidic biochips using skewed mixing trees

Reactant Minimization in Sample Preparation on Digital Microfluidic Biochips

Reactant and Waste Minimization in Multitarget Sample Preparation on Digital Microfluidic Biochips

Sample preparation for many-reactant bioassay on DMFBs using common dilution operation sharing

Volume-oriented sample preparation for reactant minimization on flow-based microfluidic biochips with multi-segment mixers

Reactant Minimization for Sample Preparation on Microfluidic Biochips With Various Mixing Models

Sample preparation for many-reactant bioassay on DMFBs using common dilution operation sharing

Graph-based optimal reactant minimization for sample preparation on digital microfluidic biochips

Sample preparation for droplet-based microfluidics

Reactant minimization during sample preparation on digital microfluidic biochips using skewed mixing trees