NDLI: Perfusion and bone mineral density as function of vertebral level at lumbar spine

Content Provider	IEEE Xplore Digital Library
Author	Ma, H.T. Haiyan Lv Griffith, J.F. Li, A.F.W. Yeung, D.K.W. Leung, J. Ping-Chung Leung Jing Yuan
Copyright Year	2012
Description	Author affiliation: Shenzhen Grad. Sch., Dept. of Electron. & Inf. Eng., Harbin Inst. of Technol., Shenzhen, China (Ma, H.T.; Haiyan Lv) \|\| Jockey Club Centre for Osteoporosis Care & Control, Chinese Univ. of Hong Kong, Hong Kong, China (Leung, J.; Ping-Chung Leung) \|\| Dept. of Diagnostic Radiol. & Organ Imaging, Chinese Univ. of Hong Kong, Hong Kong, China (Griffith, J.F.; Li, A.F.W.; Yeung, D.K.W.; Jing Yuan)
Abstract	The objective of this study is to characterize perfusion and bone mineral density (BMD) in the lumbar spine as a function of level and anatomic location. Fourteen male subjects with healthy vertebral endplates were selected to avoid gender and endplate disease influence. The bone perfusion and BMD of different vertebral level (L1-L4) were measured by the dynamic contrast enhancement MRI (DCE MRI) and the dual-energy X-ray absorptiometry (DXA) respectively. Perfusion parameters showed a significant negative correlation with upper to lower vertebral levels while inverse observation was found for BMD. The results indicated that the perfusion and BMD are as function of vertebral level and anatomic location at lumbar spine. The BMD varying with vertebral level may be determined by the biomechanical usage at the lumbar spine, where the lower levels sustain more mechanical forces. Perfusion changes along the lumbar spine level suggested that the bone marrow component could be different when BMD varies, which needs further histological verification.
Sponsorship	IEEE Eng. Medicine Biol. Soc.
Starting Page	3488
Ending Page	3491
File Size	580044
Page Count	4
File Format	PDF
ISBN	9781424441198
ISSN	1557170X
e-ISBN	9781457717871
DOI	10.1109/EMBC.2012.6346717
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2012-08-28
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Bones Spine Magnetic resonance imaging Minerals Correlation Blood
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

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