NDLI: Effect of Anesthesia on spontaneous activity and evoked potentials of the cerebellar cortex

Content Provider	IEEE Xplore Digital Library
Author	Ordek, G. Groth, J.D. Sahin, M.
Copyright Year	2012
Description	Author affiliation: New Jersey Inst. of Technol., Newark, NJ, USA (Ordek, G.; Groth, J.D.; Sahin, M.)
Abstract	Cerebellum is a highly organized structure with a crystalline morphology that has always intrigued neuroscientists. Much of the cerebellar research has been conducted in anesthetized animals, particularly using ketamine and xylazine combination. It is not clear how the cerebellar cortical circuitry is affected by anesthesia. In this study, we have recorded spontaneous and evoked potentials from the cerebellar surface with chronically implanted, flexible-substrate, multi-electrode arrays. The frequency contents of the spontaneous activity suggest that ketamine/xylazine anesthesia suppresses most of the components except those below 30 Hz. This preliminary study also showed that multi channels of cerebellar cortical activity can be recorded using flexible multi-electrode arrays in behaving animals, which is very challenging task with single microelectrodes.
Sponsorship	IEEE Eng. Medicine Biol. Soc.
Starting Page	835
Ending Page	838
File Size	522682
Page Count	4
File Format	PDF
ISBN	9781424441198
ISSN	1557170X
e-ISBN	9781457717871
DOI	10.1109/EMBC.2012.6346061
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2012-08-28
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Anesthesia Electrodes Electric potential Rats Coherence Optical fiber networks micro EcoG cerebellum and anesthesia multi-electrode arrays
Content Type	Text
Resource Type	Article
Subject	Signal Processing Biomedical Engineering Health Informatics Computer Vision and Pattern Recognition

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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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