NDLI: Molecular pattern formation and cell signaling at intermembrane junctions

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2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society

2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society

2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society

2010 Annual International Conference of the IEEE Engineering in Medicine and Biology

2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society

2008 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society

2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society

2006 International Conference of the IEEE Engineering in Medicine and Biology Society

2005 IEEE Engineering in Medicine and Biology 27th Annual Conference

The 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society

Proceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE Cat. No.03CH37439)

Proceedings of the Second Joint 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society] [Engineering in Medicine and Biology

Volume 3 - 2002

Volume 2 - 2002

Volume 1 - 2002

Mapping of chaotic patterns for localization of EEG abnormalities

Self-similarity in a human balancing task

Central and autonomic regulation of fetal heart rate: nonlinear analysis after vibroacoustic stimulation

Towards unbiased reconstruction of noisy chaotic dynamics using a robust hypersurface minimization technique

Fractal dynamics of body motion during walking in poststroke hemiplegic patients

Investigating the nonlinearity of fMRI activation data

Robust segmentation of switching dynamics in time series

Finite-time growth rate to characterize heart rate variability of idiopathic dilated cardiomyopathy patients

Reduction of electrocardiogram interference from diaphragmatic electromyogram by nonlinear filtering

Changes in the non-linear dynamics of heart rate variability due to foot based vibration while in the seated position

Nonlinear modeling of physiological systems with multiple inputs

Nonlinear advanced methods for biological signal analysis

Nonlinear EEG analysis in epilepsy: from basic research to clinical applications

Incorporating nonlinear signal analysis results in higher-level reasoning models

Hybrid fuzzy logic committee neural networks for classification in medical decision support systems

Evaluation of stress reactivity and recovery using biosignals and fuzzy theory

Similarity classification for bio-signals using fuzzy table look-up by distance and eigenvector

Next-generation decomposition of multi-channel EMG signals

Personal fitting procedure for cycle ergometer workload control by artificial neural networks

Elucidation of simple optic stimuli based on detected nerve activity

Automatic target localization using microelectrode recordings

Real-time eye blink suppression using neural adaptive filters for EEG-based brain computer interface

Power frequency and wavelet characteristics in differentiating between normal and Alzheimer EEG

A combined structural-functional classification of schizophrenia using hippocampal volume plus fMRI activation

Development of person-independent emotion recognition system based on multiple physiological signals

A neural network approach to monitor motor activities

Multi-parameters study of detecting cardiac status with nonlinear dynamics

Multifractility in labor contraction dynamics

An iterative noise reduction method for electrocardiogram

Ovarian cancer prognosis and soft computing

One-lead ECG for identity verification

Classification of EOG for human computer interface

Predictive detection methods as the next era in biological signal processing: a case study of ECG analysis

Methodology and system architecture for automated detection of epileptic seizures in the neonatal EEG

A multi-expert speech recognition system using acoustic and myoelectric signals

Logarithmic-sensitivity index as a stopping criterion for automated neural networks

An algorithm for the prediction of attendance to a breast screening unit in the UK

Comparison of methods for detection of contrast agents in ultrasound signals

Effect of wavelet denoising on time-frequency and time-scale analysis of quadrature embolic Doppler signals

Time-frequency analysis of a complicated Doppler signal with two figure eight kernels

Time-warping averaging for quantitative evaluation of changes in LV function

Ambient noise canceller in pulmonary sound using WHT transform domain adaptive filter

Short-term analysis of heart-rate variability using wavelet packets: an efficient detector of sleep apnea episodes

Cardiac rhythm tracking in electrocardiographic signals by morphological transform-based singularity detector

Dynamics of early and late phases of the phrenic neurogram during maturation

Analysis of rat electroencephalogram under slow wave sleep using wavelet transform

Wavelet analysis of normal and epileptic EEG

A wavelet based de-noising technique for ocular artifact correction of the electroencephalogram

Wavelet coherence for investigating the time-varying synchrony of EEG during sentence identification

Evoked potential generation revealed by nonstationary signal analysis

Quantifying dose-dependent changes in visual flash-induced evoked response during halothane and isoflurane anesthesia

Spatio-temporal analysis of surface electromyography signals by independent component and time-scale analysis

Change of muscle activation pattern by epidural stimulation on a SCI patient

Time-frequency modeling and classification of pathological voices

Signal processing methodologies of intracranial pressure measurements for the compliance characterization

Time-frequency identification of the slow wave in external electroenterogram

Time-frequency and time-scaling analysis of time-varying properties of renal autoregulatory mechanisms

Reconstruction of maximum blood flow velocity waveforms from Doppler ultrasound measurements

Results on the time-frequency characterization of the first heart sound in normal man

Classification of heart sounds by using wavelet transform

Derivation of respiration from ECG measured without subject's awareness using wavelet transform

Identifying voluntary components of human movement-related cortical potential using dynamic spectrum

Extraction of parameters from EMG signals for the biofeedback electrical stimulation

New method in acoustic analysis for the diagnosis of the laryngeal functions

Comparison of digital filters with wavelet multiresolution filter for electrogastrogram

Time-frequency quantification of the small bowel myoelectrical surface recording

Variable bandwidth filter for reconstruction of bio-medical signals with time-varying instantaneous bandwidth

Harmonic spectrogram for the analysis of semi-periodic physiologic signals

Changes in complexities and power spectrum of rat electroencephalogram under various anesthesia depth

Changes of event related potentials depend on the preference in pictures used for stimulations

Signal processing techniques predict characteristic frequencies of the Alzheimer's disease beta-amyloid protein and its precursor

Speaker recognition using dynamic synapse neural networks

New classes of hybrid Hadamard-wavelet transforms for signal-image processing

Removing residual power-line interference using WHT adaptive filter

The stimulations of pictures and characters cause different event related potentials

Reduction of ballistocardiogram artifact in the simultaneous acquisition of auditory event-related potentials and functional magnetic resonance images

Single trial analysis of event related potentials sensitivity of the subspace regularization based methods to the value of regularization parameter

Parameter estimation and multichannel fusion for classifying averaged ERPs

Trial modeling of the hemodynamic response using event-related fMRI

A segmented average method to increase the reproducibility of transient-evoked otoacoustic emissions

Tracking of nonstationary EEG with Kalman smoother approach: an application to event-related synchronization of alpha waves

Analysis of sleep spindles in different NREM-REM cycles by means of bispectra

EEG signal segmentation using adaptive Markov process amplitude modeling

MEG signals spatial power distribution and gamma band activity in yoga breathing exercises

A model order selection criterion for the identification of physiologic systems

Respiration rate variability between REM- and NREM-sleep

Speech features found in a continuous high order statistical analysis of speech

Feature analysis for automatic detection of pathological speech

Masked noise probability-based speech enhancement

Testing the stationarity and normality of paediatric aspiration signals

An entropy estimator with least square error [biological signals]

Using HLA sequence analysis and HLAMatchmaker to examine CREGs

A statistical approach to time frequency analysis of SEMG

Automatic detection algorithm for physiologic pressure signal components

A new approach for BAEP analysis using simulated annealing method

Modeling respiration from blood pressure waveform signals: an independent component approach

Somatosensory evoked potentials sources revealed by ICA

Independent component analysis of multichannel auditory evoked potentials

Removal of ECG artifacts from EEG using ICA

Multi-channel analysis of the EEG signals and statistic particularities for epileptic seizure forecast

Study of the electrical activity of heart cells by simulation with mathematical models

Noninvasive cardiac output monitoring based on multichannel blind system ID and modal decomposition

An optimal term selection scheme for the Volterra system model applied to the analysis of heart rate fluctuations

Gender differences in voluntary cough sound spectra demonstrated by an inverse power law analysis

Nonlinear modeling of the insulin-glucose dynamic relationship in dogs

Type I diabetes: modeling, identification and non-linear model predictive control

Modeling interstitial glucose kinetics in subjects with type I diabetes during physiological conditions

Computational modeling of depth-EEG signals observed in interictal to ictal transition in human temporal lobe epilepsy

Self-organized criticality in the epileptic brain

Modeling of auditory evoked potentials

A self-organizing model of chemotopic convergence for olfactory coding

Analysis of cerebellar flocculus Purkinje cell firing patterns during visual vestibular interactions before and in the process of VOR motor learning

A spatiotemporal dipole simulation of biomagnetic fields from gastric electrical activity

Respiratory and muscular analysis in patients with OSAS at different levels of ventilatory effort

Comparison of malfunction diagnosis sensibility for direct and inverse ECG signal processing methods

Preliminary prediction of flow and particulate concentration produced from normal human cough dispersion

Action potential heterogeneity assists frequency entrainment in the intact cardiac pacemaker

Translation and rotation invariance of physiological signal in long-term custody

Modeling the cyclic relationship between myoplasmic [Ca/sup 2+/] and isovolumic LVP in guinea-pig intact hearts

A biodynamical regulatory model of the human T-cell system

Using autoregressive spectral analysis to investigate weaning index

Modeling fluctuations in relative axial progress

Short term adaptation exists in the disparity vergence system exhibited by a decrease in the response dynamics

Three-dimensional biomechanical model of benign paroxysmal positional vertigo

Finite element modeling of human ear with external ear canal and middle ear cavity

Computer-aided 3-dimensional modeling of human ear

A lumped-parameter mechanical model of human ear for sound transmission

Neural excitation patterns of four cochlear implant electrode array configurations

A new approach to closed-loop linear system identification via a vector autoregressive model

A computational investigation of the role of angiogenic inhibitors in tumor-induced angiogenesis

Estimation and localization of electrical dipoles in somatosensory evoked potentials

Transform domain adaptive enhancement filter for evoked potential

A simultaneous filtering and feature extraction strategy for direct brain interfacing

Eye tracking using deformable model

Estimating brain compliance based on a novel model of intracranial cerebrospinal fluid dynamics

Advances in model-based closed-loop control of hypnosis

The leg drop pendulum test under anesthesia. I. Normal limbs, awake vs. asleep

Preserving acoustic cues in speech denoising

Establishment of an electrical thermal model based on the ASHRAE standard

Effects of membrane undulations on contact time in cell adhesion

Traction stresses and motility of fibroblasts are different on RGD- and fibronectin-modified elastic substrata

The leading edge is the primary force producing component of migrating fibroblasts

Quantitative measurements of active and passive mechanical properties of adult cardiac myocytes

Effect of mechanical stretch and shortening on the stiffness of human aortic endothelial cells

Micromechanical properties of isolated nuclei and nuclear components

Electromechanical effects on nanotube formation from lipid membranes

Response of endothelial cells to combined fluid shear stress and cyclic strain

The contribution of adhesion forces to the leukocyte response to shear stress

Role of directionality of pulsatile strain on cell shape and JNK activation

Mechanical regulation of anterior cruciate ligament cell function and gene activity

Regulation of bone-associated genes in smooth muscle with mechanical strain

Wall shear stress regulation of occludin expression in human umbilical vein endothelial cells

Morphological differences between aortic and aortic valve endothelial cells in static and fluid flow conditions

Rapid, multipoint molecular spectroscopic measurements of shear effects on endothelial cell membranes

Flow-induced strain focusing in the endothelial cytoskeleton

The molecular dynamics of focal adhesion kinase in the mechanotaxis of endothelial cell migration

Prototype of a rapid assay for cellular mechanotransduction

Kidney cell mechanotransduction in response to sustained hydrostatic pressure

Effects of angiotensin II on cardiac fibroblast contractility

Cellular and molecular features that stabilize rolling on selectins under flow

Membrane tether formation by rolling neutrophils on E-selectin

The effect of applied force on neutrophil contact area

Mechanical properties of the P-selectin/PSGL-1 interaction

Using direct force measurements to determine the mechanism of neural cell adhesion molecule (NCAM) function

Micropeel dynamics of cells - correlations with substrate compliance and cytoskeletal structures

Cell tracking velocimetry for monocyte/endothelial cell interactions

Dynamics of surface receptor interactions required for an immune response

Estimation of the platelet glycoprotein (GP) Ib - von Willebrand factor (vWf) bond lifetime under hydrodynamic flow

Selectin-like kinetics and biomechanics promote rapid platelet adhesion in flow: the GPIb/spl alpha/-vWF tether bond

Increased numbers of bonds stabilize adhesion with multiple tethers between endothelium and monocytes

Adhesive interactions of erythrocytes with neutrophils, platelets and fibrin: Implications for deep vein thrombosis

Formation of adhesive contacts between neutrophils and beads coated with endothelial ligands

Molecular dynamics simulations of charged plates and electrolyte in a bilayer-like geometry: molecular ordering and electrostatic potential

Displacement field of the cytoskeleton in response to a local load

Phase diagrams of membrane skeletons based on liquid crystal elastomer simulations

Modeling shear stress sensing and transmission in vascular endothelial cells

The structure and stability of microtubules

Cell adhesion modeling: effect of leukocyte rheology

Structural optimization analysis of endothelial cell remodeling to fluid flow

Balance and modes of energy in the piezoelectric cochlear outer hair cell wall

Effect of outer hair cell membrane piezoelectric properties on the receptor potential under high-frequency conditions

Stent graft treatment optimization in a computer guided simulation environment

Influence of vessel geometry on leukocyte adhesion: a Lattice-Boltzmann model

Shear stress distributions on the membrane of endothelial cells using 3-D computational modeling with fluid-structure interactions

A numerical analysis of the mechanosensory hypothesis of brush border microvilli

Single cell micromanipulation using magnetic beads: a computational model

Calcification by vascular cells is regulated by mechanical strain and MAPK signaling

Aortic smooth muscle cells respond to soluble proteins released by aortic endothelial cells after fluid flow exposure

Reorientation response of endothelial cells to cyclic compression: comparison with cyclic stretching

Culturing smooth muscle cells on modified PDMS substrates

Simulation of platelet deposition in disturbed flow

Effects of membrane undulations on contact time and area in cell adhesion

Application on advanced optical tweezers to the study of mitotic motor proteins

Effect of salicylate on membrane electromechanics

Finite strain analysis for biaxial isotropic flexible cell culture membranes

The effects of the actin cytoskeleton on the transverse mechanical properties of skeletal muscle cells

Cells on gels: smooth and skeletal muscle cell responses to substrate compliance

Determining material properties of the embryonic chick heart during cardiac looping morphogenesis

Effects of diabetes mellitus on the biomechanical properties of the female rat urethra

Macromolecular orientation and tissue mechanics: a comparative study of blood vessels, skin and tendon

Mechanical stresses associated with airway reopening injury of pulmonary epithelial cells

Directional permeability in a porcine carotid elastin biomaterial vascular conduit

A mechanism for the size-related differences in mechanical properties of mitral valve chordae

The influence of tensile and compressive damage on bending fatigue of human cortical bone

Interrelationship of trabecular mechanical and microstructural properties

Bone-implant interface in a rabbit femur model in vivo: nanoscopic mineralization patterns by atomic force microscopy

Mechanically induced changes in trabecular bone architecture

Age-related changes in cortical bone toughness: initiation vs. propagation

In situ tensile load modulates inhibition of MMP-1 expression in tendons cells

Regulating signaling and gene expression in tendon cells with mechanical load

Peering from the outside in: viscoelastic properties of the extracellular matrix dictate spatial organization and apoptosis resistance in mammary epithelial cells

Mechanical and structural changes in diabetic rat peripheral nerve collagens

A growth and remodeling mixture model and the biomechanics of developing bovine articular cartilage

Growth of cartilage explants in long-term: free-swelling culture: biochemical and tensile biomechanical properties

Static compression inhibits matrix protein gene expression and increases collagenase gene expression in the meniscus

Biomechanical behavior of the temporomandibular joint disc

Biomechanical properties of the medial meniscus in experimental animal models

Use of carbomethylcellulose to improve the mechanical and handling characteristics of calcium sulfate bone graft material

Micro-mechanical testing of bone tissues in secondary osteon and interstitial bone regions

A mouse model for hand-arm vibration syndrome

A model for pressure enhancement in the diabetic nerve: simulations of diabetic rat peripheral nerve and nerve collagens

Computational modeling of a triaxial test for soft tissues

Do cement lines restrict osteoclastic bone resorption?

The structural response of trabecular bone to low-level mechanical stimuli

Adaptation of a single trabecula to a changing stress environment

Promotion of bony ingrowth by low intensity high frequency oscillatory intramedullary pressure stimulation

Trabecular bone formation induced by high frequency, low intensity oscillatory intramedullary pressure stimulation

Molecular design and cellular studies with oral insulin delivery systems

Controlled release and stealthy circulation of polymersomes

Bioerodible polyanhydrides with tailored microstructure for controlled drug delivery

Development of multilayered sintered microsphere coatings to create unique delivery profiles

Controlled release of a tissue inducing peptide from oligo(poly(ethylene glycol) fumarate) hydrogels for orthopedic tissue engineering

Tissue engineering scaffolds for controlled protein and plasmid delivery

Nitric-oxide generating hydrogels inhibit intimal thickening and promote endothelial cell proliferation

Bioactive delivery systems for nerve regeneration

The development of fibrin-based scaffolds for spinal cord regeneration

Fibrin-mediated delivery of KGF in 2D and 3D models of wound regeneration

Guidance channel development: controlled release of NGF from PLGA scaffolds

Design and synthesis of novel pH and temperature sensitive copolymers for injectable delivery

Use of complexation hydrogels for oral delivery of chemotherapeutic agents

Pulsatile release of insulin via photothermally modulated drug delivery

Ultrasound-enhanced drug delivery for efficient cancer therapy

Peroral insulin delivery using complexation gels

Surface-preferential crosslinking in hydrogels to minimize the burst effect and design tunable lag times for drug delivery

The mechanics of microneedles

Tailored drug release profiles from bioerodible polyanhydride microspheres

Applications of the electrostatic layer-by-layer self-assembly technique in biomedical engineering

Nanoparticles and ultrasound for delivery of model macromolecular anti-cancer drugs in tumors

Effects of microneedle tip geometry on injection and extraction in the skin

Incorporating dexamethasone release in hydrogel coated microdialysis probes

Adhesive block copolymers for tissue repair and drug delivery

Mechanistically-based pharmacodynamics: molecular response to geldanamycin derivatives in human tumor xenographs

Modeling release from degradable PEG hydrogels and their application in the delivery of osteoinductive growth factors

Transscleral diffusion of ethacrynic acid and sodium fluorescein

Effects of tissue stretching or cell shrinkage on penetration depth of macromolecules in a rat fibrosarcoma

Dynamic behavior of nerve growth factor upon administration to the rat brain parenchyma

Dynamics of fibrin clot lysis under flow conditions by erythrocyte-linked tPA

Biodegradable artificial leukocyte for targeted drug delivery

Elastin-like polypeptide-doxorubicin conjugates for cancer therapy

Targeting microparticles to select tissue via radiation induced upregulation of endothelial cell adhesion molecules

Localized delivery of anti-heparanase for inhibition of restenosis

Targeted photothermal tumor therapy using metal nanoshells

Polymeric vehicles for locally presenting tissue inductive molecules

Gene therapy in tissue engineering

Retrovirus-polymer complexes increase virus binding and the efficiency of gene transfer

An experimental system for the analysis of targeted retrovirus transduction

Macromolecular transport through arterial wall: elastic barrier permeabilities

Lentivirus vector pseudotyped with human parainfluenza virus type 3 glycoproteins

Formulation and characterization of biodegradable hyaluronan (HA) gene delivery films

Rate-limiting steps in retrovirus production and gene transfer

Effects of electric pulse strength and pulse duration on plasmid DNA electromobility

Real-time quantitation of intracellular polycation/DNA nanocomplex transport: evidence for directed motion

Cationic corticosteroid vehicle for gene delivery

New degradable cationic polyesters for nonviral gene delivery

Characterization of an electrospun poly(lactide-co-glycolide) and block copolymer-based, nanostructured matrix for DNA delivery

Phage display of adenoviral HI loop for "context-specific" ligand selection

Delivery of PEI-condensed DNA via a porous polymer scaffold for tissue engineering applications

Tissue-Engineered Liver Microreactor as an in vitro surrogate assay for gene delivery (Ad.CMV.EGFP delivery)

Efficient retroviral gene transfer to epidermal stem cells on recombinant fibronectin

Optimization of PEI/VEGF DNA polyplexes for potenital delivery from tissue engineering scaffolds

Reducing systemic toxicity in local tumor gene therapy using an alginate solution

Development of novel poly(ethylene glycol) based vehicles for gene therapy

Bioengineered polymeric substrata to probe cell behavior during vascular remodeling

Amplification of biomolecular interactions using liquid crystals and nanostructured surfaces

Integrin-specific bioadhesive surfaces using a triple-helical collagen-mimetic peptide

A colorimetric gold nanoparticle biosensor: effect of particle size on sensitivity

Comparing vascular smooth muscle cell population migration on various surface chemistry modifications

The effects of adhesivity on cell migration through biomimetic matrices

Receptor-cytoskeletal unbinding in detachment of P-selectin from PSGL-1 on leukocytes

Spatial mapping of membrane phases in confluent endothelial cells

Fluid shear-induced membrane fluctuations measured by laser dark field microscopy

Molecular pattern formation and cell signaling at intermembrane junctions

Cholesterol-rich plasma membrane microdomains regulate integrin mediated mechanotransduction

A new understanding of osteocyte process ultrastructure

Interdomain interactions in the KIF3 kinesin family motor

Tracking of displacement steps generated by single myosin ID and myosin II molecules

Watching single RNA molecules respond to local application of mechanical force

Integrated modeling of yeast kinetochore microtubule dynamics and the imaging thereof by fluorescence microscopy

Probing the conformations of fibronectin in cell culture

Low force cooperativity in the extensible unfolding of cytoskeletal proteins

Conformational changes in fibronectin due to adsorption to well-defined surface chemistries

Surface chemistry modulates integrin binding, focal adhesion assembly and matrix mineralization

Explicit counterions in actin polymerization simulations

"Marker of self" CD47: from erythrocyte to drug delivery

Coating bio-nanofilm on PDMS through layer-by-layer self-assembly

Characterization of molecular and cellular events limiting the effectiveness of antisense oligonucleotides

Supramolecular structure of a helical ribbon peptide self-assembly

Mutational analysis verifies that "kneed" sequence of fibronectin participates in cell-substrate interactions

Design of Fc-conjugated protein therapeutics using computational modeling of protein-protein interaction energetics

Assessment of the efficacy of tissue factor pathway inhibitor (TFPI) immobilized on glass slides to inhibit factor Xa under flow conditions

Assessment of monocyte derived dendritic cell phenotype upon biomaterial contact in vitro

Characterization and optimization of a novel design to increase the haemocompatibility of biomaterials

Osteoblast response to alumina and titania nanometer wear debris

Increased adhesion on carbon nanofiber/polymer composite materials

Viscosity sensitivity in a reversible polyacrylamide gel with DNA crosslinks

Multi-color single filter photobleaching analysis for measuring gene expression

Fluorescence lifetime spectroscopy in multiply scattering media

Sampling volume probed by frequency-domain photon migration measurements

Oxidative stress and lipid peroxidation due to endothelial cell exposure to fluid shear stress

Shear-induced dissociation of Gaq-PECAM-1 at endothelial cell junctions

Shear stress regulates endothelial NO synthase (eNOS) by the protein kinase A (PKA)-dependent mechanisms

Transduction of compressive stress by bronchial epithelium

Arterial shear stress frequency regulates the mechanosensitive discrimination of endothelial responsiveness

Studies of shear stress alterations in gene expression in endothelial cells shown by DNA microarray

The shear threshold effect for adhesion through L-selectin: influence of receptor and ligand site density

Shear stress-induced cytoskeletal rearrangement involves caveolae-mediated mechanotransduction

Shear stress activation of the glucocorticoid receptor transcription pathway

Fluid shear stress inhibits vascular smooth muscle cell migration in vitro

Microarray analysis of the chondrocytic cell line T/C-28a2 under dynamic fluid shear

cDNA microarray analysis of human umbilical vein endothelial cells subjected to cyclic mechanical strain

Multi-directional flow chamber: analysis of endothelial cell morphology dependence on differential shear forces

An in vitro tissue culture model for interstitial flow

Microsensors to characterize shear stress regulating inflammatory responses in the arterial bifurcations

Effect of hydrostatic pressurization on chondrocyte differentiation

Identification of a novel gene isolated from a fracture callus

Zonal separation of articular cartilage

Affinity and kinetic analysis of L-selectin binding to their natural ligands and to synthetic oligosaccharides

Dynamics of Type IIb mutation-induced conformational changes in the von Willebrand factor Al domain

Effect of shear stress on platelet activation via the glycoprotein VI receptor

Force history dependence of reverse-rates of P-selectin interacting with PSGL-1

Mycological culture in microchannels

Differential effects of lactacystin on IL-1 beta and TNF-alpha induced adhesion molecule expression and myeloid cell adhesion to endothelial cells

Differentiation of mouse epl (early primitive ectoderm like) cells into endothelial progenitors

The influence of cyclic strain on the differentiation of rat bone marrow derived mesenchymal stem cells to vascular smooth muscle

In vivo assessment of bone marrow cell implantation in reconstructive surgery using microcirculatory experimental models

Cytotoxicity of redox radical initiators for encapsulation of mesenchymal stem cells

A manipulator with flexible drilling unit for hematopoietic stem cell harvesting

Directed attachment of Schwann cells on protein micropatterned degradable polymeric substrates

A model for growth cone guidance by attractive or repulsive cues

Cell adhesion ligands allow neurite extension on polyethylene glycol hydrogels

Potential role of transport in the affect of nitric oxide on thrombus formation

Continuous observation of heat shock protein 70 expression in its kinetics study

Purification and characterization of Archaeoglobus fulgidus shikimate 5-dehydrogenase

Cytocidal and inhibitory effect of energy-controllable pulse on ovarian cancer cell line SKOV3

An in vitro study of antibody-induced inhibition and detachment of Staphylcocci from fibrinogen

Shear prevents detachment of target cells bound to E. coli via the bacterial adhesin, FimH

Fluid shear influences binding magnitude of S. aureus suspended in blood to collagen

Vitronectin receptor stimulation of remote vascular responses: role of connexin 43

Multiaxial thermal damage of collagenous membranes

Modeling cellular thermal damage from radio-frequency ablation

The effects of streptavidin-biotin exogenous ligands on the endothelium-derived nitric oxide synthase activity

Imaging and quantitative analysis of phosphoinositide 3-kinase signaling in living fibroblasts

Statistical and deterministic methods for reverse engineering biological pathways

Stochastic modeling of spatially localized events in protein kinase A and Ca/sup 2+/ signaling

Modeling of feedback interactions between MAP kinase and cAMP signaling pathways

Application of multivariate analysis for optimizing & predicting hepatic function

Model for microtubule chemotaxis

Characterizing L-selectin/PSGL-1 interactions using an atomic force microscope

Conformational activation of 2 integrins, their I domains, and regulation by small molecule antagonists

Yeast surface display of cell adhesion molecules: a tool for molecular evolution and cellular motion characterization

Fluid shear modulates the molecular interactions between polymorphonuclear leukocytes and colon carcinomas

Inhibition of ICAM-mediated monocyte adhesion with a bioresponsive dextran-based conjugate

Expression of ICAM-1 and E-selectin in irradiated cerebral microvasculature

A systems biology approach to hematopoietic stem-cell differentiation

Adult stem cell differentiation: what does it mean?

The role of sonic hedgehog in adult neural progenitor cell proliferation in vitro and in vivo

Scalable generation of cardiomyocytes from mouse embryonic stem cells

Endothelial progenitor cells from embryonic stem cells

Neovasculature in bone marrow stem cell mobilization for treating myocardial infarction

Modeling stem cell population growth: incorporating parameters for quiescence, differentiation and apoptosis

Clincal experience with an ECM scaffold for tissue engineering

Directing tissue regeneration via hyaluronic acid hydrogel scaffolds

Enhanced functions of cells on polymers with nanostructured surfaces

Cytocompatibility of preadipocytes in diacrylated polyethylene glycol crosslinked with various UV light photoinitiating systems

Development of a cell-delivery vehicle derived from electrospun non-woven nanostructured membranes

Development of a highly porous, flexible and biodegradable poly(ester urethane)urea scaffold for tissue engineering

Preadipocyte adhesion and migration dynamics on ECM proteins

Engineering cell motility via substrate incorporation of poly(ethylene glycol)

Dynamic seeding of tissue-engineered vascular grafts in a novel perfusion bioreactor system

Adaptation of endothelial cells in arteries under axial stretch in organ culture

Role of proliferation in endothelial cell monolayer formation

Genetic modification of smooth muscle cells to enhance mechanical properties of tissue engineered constructs

Gene expression profiling in engineered skin substitutes subjected to chemical injury: protective effects of keratinocyte growth factor

Hepatocellular engineering via acellular cadherin-derived microinterfaces

In vitro primary hepatocyte proliferation with nonparenchymal liver cell activation

Gene expression profiling to explore mechanisms of cell-cell interaction in hepatic co-cultures

Passaging effects on mineralization and mRNA expression of rat calvarial cells seeded in monolayer and on 3D polymer constructs in vitro

In vitro differentiation of neonatal foreskin fibroblasts to chondrocytes

Tissue engineering: harvesting pericardial cells from human pericardium

Cardiac cell networks on elastic microgrooved scaffolds

The effect of cell culture substrate on cell tolerance to desiccation

Media composition affects the survival of desiccated mammalian cells

Reconditioning of fatty livers for transplantation increased survival of recipients in a rat model

Effect of sepsis after burn injury on the dynamics of granulopoiesis in mice

Pancreatic enzyme mechanisms that trigger physiological shock and high mortality

Integrin-mediated cell adhesion to fibronectin: initial binding and strengthening responses

Regulation of lymphatic vessel formation by interstitial fluid forces

In vitro degradation of in situ crosslinkable poly(propylene fumarate-co-ethylene glycol)-based macroporous hydrogels

Alginate matrices to regulate granulosa cell morphology and steroid production

Micro-engineered biomineralized materials for bone tissue engineering

Compositional effects on albumin system properties

Composite tissue-engineered materials

Tissue engineered vascular grafts: elastic polyethylene glycol hydrogel scaffolds for culture under pulsatile flow conditions

Tethered basic fibroblast growth factor increases vascular cell proliferation

Collagen, fibrin and collagen-fibrin mixtures as matrix materials for vascular tissue engineering

Tissue engineering of intact arterial segments by directed remodeling

Development of a YIGSR peptide-modified polyurethaneurea to enhance endothelialization

Controlled degradation of peptide modified hydrogels improves rate, quality, and quantity of in vivo bone formation

Quantitative Micro-CT analysis of mineralized matrix formation on natural and synthetic 3D scaffolds in vitro

Immunohistochemical characterization of guided bone formation by a biodegradable tissue engineering scaffold in a healing tooth socket of a rabbit model

A two-step chondrocyte recovery system based on thermally sensitive elastin-like polypeptide scaffolds for cartilage tissue engineering

Modeling tissue ablation with radio frequency heating: effect of blood flow in a large vessel

Monte Carlo simulation of freezing of confluent tissues

Dynamic loading increases strength of tissue-engineered chordae tendineae

Development of a pulsatile-flow tissue engineered heart. Valve bioreactor system to mimic the physiological function of the human left heart

Changes in the structure and biosynthetic activity of porcine heart valve leaflets under elevated pressure

A charge-filtration-diffusion model for microvessel permeability

A simple, non-invasive technique to monitor the biomechanical properties of ex vivo cultured blood vessels

Noninvasive determination of perfused blood vessel dimensions using a pressure-diameter relationship

Computation of the fluid-induced shear stress in bioreactor-cultured 3D cell systems

Design of a single capillary-parenchymal co-culture bioreactor

Establishing a system for the study of urethral biomechanical function

Modeling of balloon endometrial ablation

A novel bioreactor for the dynamic flexural stimulation of tissue engineered heart valve biomaterials

In-vitro synthesis of elastin sheets on crosslinked hyaluronan gels for tissue engineering of aortic valves

Biodegradable amino acid-hydrogel porous scaffold for the tissue engineering of the heart valve

Development and characterization of improved tissue engineered valve-equivalents using chemical and mechanical signaling

Designing scaffolds for valvular interstitial cells

A critical appraisal for the clinical future of tissue engineered blood vessels (TEBV)

Evaluation of collagen-elastin hybrid tissue engineered vascular constructs

Val-Ala-Pro-Gly, an elastin derived non-integrin ligand: cell adhesion and specificity

Development of fibrin-based tissue engineered vessels

Tissue-engineered microvascular networks for gene therapy made from adult endothelial and endothelial progenitor cells

Stimulation of in vivo angiogenesis by cytokine-loaded hyaluronic acid hydrogel implants and potential gene expression mechanisms for new vessel growth

Fluid dynamics of bioreactors for tissue engineered cartilage

In vivo experience with an extracorporeal flat-plate bioartificial liver: demonstration of efficacy in treating fulminant hepatic failure

Dermagraft/sup /spl reg// scale-up case study

Manipulation of adult bone marrow derived stem and progenitor cell population. Dynamics in suspension culture

Engineering human tissues for in vivo applications: storage and translational issues for tissue repair and regeneration

Fluid flow increases mineralized matrix deposition in three-dimensional perfusion culture of marrow stromal osteoblasts in a dose-dependent manner

A combination approach to engineering bone regeneration: Biomineral presentation and induced angiogenesis

Effect of media perfusion rate on cell seeded 3D bone constructs in vitro

Controlling mineralized tissue formation and distribution by osteoblasts photoencapsulated in PEG hydrogels

Induced cell clustering enhances islet /spl beta/ cell formation from pancreatic ductal epithelial cells

Single tether formation from unstimulated microvascular endothelial cells

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Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society

Molecular pattern formation and cell signaling at intermembrane junctions

Content Provider	IEEE Xplore Digital Library
Author	Groves, J.T.
Copyright Year	2002
Abstract	Summary form only given. Spatial organization of proteins is an emerging theme of broad significance in cell recognition and signal transduction. Cells from the immune system and nervous system, among others, engage target cells through highly organized patterns of proteins that assemble at the intercellular synapse. Though still controversial, there is mounting evidence indicating that specific synaptic patterns correlate with cellular activation. We are exploring the physical mechanisms behind synaptic pattern formation at intermembrane junctions in an effort to elucidate their role in cell recognition and signaling. The fundamental problem we address is the collective interaction of populations of receptors and ligands in apposing lipid bilayer membranes. In order to address this problem experimentally, we have initiated development of a totally reconstituted inter-membrane junction between a supported membrane and a second membrane patch, which is deposited from a giant vesicle. Incorporation of different fluorescent probe lipids into each of the two membranes enables a variety of fluorescence imaging capabilities which we employ to obtain both lateral and topographical information about the junction. Intermembrane resonance energy transfer and optical standing wave interferometry is discussed.
File Size	41792
File Format	PDF
ISBN	0780376129
ISSN	1094687X
DOI	10.1109/IEMBS.2002.1136963
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2002-10-23
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Pattern formation Biomembranes Proteins Lipidomics Fluorescence Optical interferometry Immune system Nervous system Assembly systems Pattern recognition
Content Type	Text
Resource Type	Article

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