NDLI: Internal limiting membrane peeling versus no peeling for idiopathic full-thickness macular hole: a pragmatic randomized controlled trial.

Please wait, while we are loading the content...

Quantification of the therapeutic response of intraretinal, subretinal, and subpigment epithelial compartments in exudative AMD during anti-VEGF therapy.

Morphometric characteristics of central retinal artery and vein endothelium in the normal human optic nerve head.

Fixation stability during binocular viewing in patients with age-related macular degeneration.

Visual acuity development of children with infantile nystagmus syndrome.

Assessment of the contribution of cytokine plasma levels to detect retinopathy of prematurity in very low birth weight infants.

Immunohistochemical evidence of synaptic retraction, cytoarchitectural remodeling, and cell death in the inner retina of the rat model of oygen-induced retinopathy (OIR).

Revealing Henle's fiber layer using spectral domain optical coherence tomography.

The effect of ageing on in vivo human ciliary muscle morphology and contractility.

Cone structure in retinal degeneration associated with mutations in the peripherin/RDS gene.

Integrin-Linked Kinase Regulates Integrin Signaling in Human Trabecular Meshwork Cells

In vitro interactions of Fusarium and Acanthamoeba with drying residues of multipurpose contact lens solutions.

Total corneal power estimation: ray tracing method versus gaussian optics formula.

Differentially expressed genes associated with human limbal epithelial phenotypes: new molecules that potentially facilitate selection of stem cell-enriched populations.

Activation of P2X Receptors Induces Apoptosis in Human Retinal Pigment Epithelium

Claudin-19 and the Barrier Properties of the Human Retinal Pigment Epithelium

Effect of elevated intracellular cAMP levels on actomyosin contraction in bovine trabecular meshwork cells.

Figure ground discrimination in age-related macular degeneration.

Polarized secretion of PEDF from human embryonic stem cell-derived RPE promotes retinal progenitor cell survival.

Three-dimensional imaging of macular inner structures in glaucoma by using spectral-domain optical coherence tomography.

Low Levels of Hydrogen Peroxide Stimulate Corneal Epithelial Cell Adhesion, Migration, and Wound Healing

Transcriptional regulation of activating transcription factor 4 under oxidative stress in retinal pigment epithelial ARPE-19/HPV-16 cells.

The use of mucoadhesive polymers to enhance the hypotensive effect of a melatonin analogue, 5-MCA-NAT, in rabbit eyes.

In vivo efficacy of bone marrow stromal cells coated with beta-tricalcium phosphate for the reconstruction of orbital defects in canines.

Non-damaging retinal phototherapy: dynamic range of heat shock protein expression.

Relationship of central corneal thickness with optic disc parameters: the Singapore Malay Eye Study.

Prophylactic effect of intravenous moxifloxacin in a rabbit model of Staphylococcus epidermidis endophthalmitis.

Dissection of chromosome 16p12 linkage peak suggests a possible role for CACNG3 variants in age-related macular degeneration susceptibility.

The effect of graded cyclic stretching on extracellular matrix-related gene expression profiles in cultured primary human lamina cribrosa cells.

Outflow physiology of the mouse eye: pressure dependence and washout.

The Impact of Vision Impairment for Children (IVI_C): validation of a vision-specific pediatric quality-of-life questionnaire using Rasch analysis.

Therapeutic effect of stealth-type polymeric nanoparticles with encapsulated betamethasone phosphate on experimental autoimmune uveoretinitis.

TNFalpha is required for late BRB breakdown in diabetic retinopathy, and its inhibition prevents leukostasis and protects vessels and neurons from apoptosis.

Association of birth parameters with OCT measured macular and retinal nerve fiber layer thickness.

In vivo confocal microscopic evidence of keratopathy in patients with pseudoexfoliation syndrome.

Generation of Cre transgenic mice with postnatal RPE-specific ocular expression.

Geranylgeranylation facilitates proteasomal degradation of rho G-proteins in human trabecular meshwork cells.

Eye-hand coordination skills in children with and without amblyopia.

The therapeutic impact of perceptual learning on juvenile amblyopia with or without previous patching treatment.

Longitudinal change detected by spectral domain optical coherence tomography in the optic nerve head and peripapillary retina in experimental glaucoma.

Long-term in vivo imaging and measurement of dendritic shrinkage of retinal ganglion cells.

Lack of TNF-alpha promotes caspase-3-independent apoptosis during murine cytomegalovirus retinitis.

Hemianopic and quadrantanopic field loss, eye and head movements, and driving.

Sclera as a surrogate marker for determining AGE-modifications in Bruch's membrane using a Raman spectroscopy-based index of aging.

Genetic variants associated with optic nerve vertical cup-to-disc ratio are risk factors for primary open angle glaucoma in a US Caucasian population.

Choriocapillaris vascular dropout related to density of drusen in human eyes with early age-related macular degeneration.

Assumption constraints of fluorophotometry in human eyes.

Cell-deposited matrix improves retinal pigment epithelium survival on aged submacular human Bruch's membrane.

Tumor necrosis factor-alpha mediates photoreceptor death in a rodent model of retinal detachment.

Dark matters in AMD genetics: epigenetics and stochasticity.

How should we measure the ciliary muscle?

Understanding autoimmune uveitis through animal models. The Friedenwald Lecture.

Author response: On the presence of (O-acyl)-omega-hydroxy fatty acids and their esters in human meibomian gland secretions.

Year: 2011 Volume: 52 Issue: 2

Year: 2011 Volume: 52 Issue: 1

Year: 2010 Volume: 51

Year: 2009 Volume: 50

Year: 2008 Volume: 49

Internal limiting membrane peeling versus no peeling for idiopathic full-thickness macular hole: a pragmatic randomized controlled trial.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Vale, Luke McDonald, Alison Cook, Jonathan Ternent, Laura Boachie, Charles McPherson, Gladys Lois, Noemi Burr, Jennifer Norrie, John
Description	Country affiliation: United kingdom Author Affiliation: Lois N ( Ophthalmology Department, Grampian University Hospitals-NHS (National Health Service) Trust, Aberdeen, United Kingdom. noemilois@aol.com)
Abstract	PURPOSE: To determine whether internal limiting membrane (ILM) peeling is effective and cost effective compared with no peeling in patients with idiopathic stage 2 or 3 full-thickness maculay hole (FTMH). METHODS: This was a pragmatic multicenter randomized controlled trial. Eligible participants from nine centers were randomized to ILM peeling or no peeling (1:1 ratio) in addition to phacovitrectomy, including detachment and removal of the posterior hyaloid and gas tamponade. The primary outcome was distance visual acuity (VA) at 6 months after surgery. Secondary outcomes included hole closure, distance VA at other time points, near VA, contrast sensitivity, reading speed, reoperations, complications, resource use, and participant-reported health status, visual function, and costs. RESULTS: Of 141 participants randomized in nine centers, 127 (90%) completed the 6-month follow-up. Nonstatistically significant differences in distance visual acuity at 6 months were found between groups (mean difference, 4.8; 95% confidence interval [CI], -0.3 to 9.8; P = 0.063). There was a significantly higher rate of hole closure in the ILM-peel group (56 [84%] vs. 31 [48%]) at 1 month (odds ratio [OR], 6.23; 95% CI, 2.64-14.73; P < 0.001) with fewer reoperations (8 [12%] vs. 31 [48%]) performed by 6 months (OR, 0.14; 95% CI, 0.05-0.34; P < 0.001). Peeling the ILM is likely to be cost effective. CONCLUSIONS: There was no evidence of a difference in distance VA after the ILM peeling and no-ILM peeling techniques. An important benefit in favor of no ILM peeling was ruled out. Given the higher anatomic closure and lower reoperation rates in the ILM-peel group, ILM peeling seems to be the treatment of choice for idiopathic stage 2 to 3 FTMH. (Clinical Trials.gov number, NCT00286507.).
ISSN	01460404
e-ISSN	15525783
Journal	Investigative Opthalmology & Visual Science
Issue Number	3
Volume Number	52
Language	English
Publisher	Association for Research in Vision and Ophthalmology
Publisher Date	2011-03-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Epiretinal Membrane Surgery Retinal Perforations Vitreoretinal Surgery Contrast Sensitivity Physiology Cost Of Illness Cost-benefit Analysis Physiopathology Fluorescein Angiography Fluorocarbons Administration & Dosage Health Resources Utilization Phacoemulsification Quality-adjusted Life Years Tomography, Optical Coherence Visual Acuity Vitrectomy Comparative Study Multicenter Study Randomized Controlled Trial Research Support, Non-u.s. Gov't Discipline Ophthalmology
Content Type	Text
Resource Type	Article
Subject	Ophthalmology Sensory Systems Cellular and Molecular Neuroscience

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

The Effect of Internal Limiting Membrane Peeling in Epiretinal Membrane Including Pseudolamellar Macular Hole

A study analyzing macular microvasculature features after vitrectomy using OCT angiography in patients with idiopathic macular epiretinal membrane

Accidental Subretinal Brilliant Blue G Migration During Internal Limiting Membrane Peeling Surgery

Progressive changes of regional macular thickness after macular hole surgery with internal limiting membrane peeling.

Delayed Closure of Idiopathic Macular Hole after Vitrectomy, Internal Limiting Membrane Peeling, and Gas Tamponade

Effect of Macular Internal Limiting Membrane Peeling on Single Surgery Success Rates of Vitrectomy for Uncomplicated, Primary Macula-Off Retinal Detachment

Vitrectomy for the removal of idiopathic epiretinal membrane with or without internal limiting membrane peeling: a meta-analysis

Pars plana vitrectomy with and without peeling of the inner limiting membrane (ILM) for diabetic macular edema.

Re-operation of idiopathic full-thickness macular holes after initial surgery with internal limiting membrane peel.

Internal limiting membrane peeling versus no peeling for idiopathic full-thickness macular hole: a pragmatic randomized controlled trial.

Similar Documents

The Effect of Internal Limiting Membrane Peeling in Epiretinal Membrane Including Pseudolamellar Macular Hole

A study analyzing macular microvasculature features after vitrectomy using OCT angiography in patients with idiopathic macular epiretinal membrane

Accidental Subretinal Brilliant Blue G Migration During Internal Limiting Membrane Peeling Surgery

Progressive changes of regional macular thickness after macular hole surgery with internal limiting membrane peeling.

Delayed Closure of Idiopathic Macular Hole after Vitrectomy, Internal Limiting Membrane Peeling, and Gas Tamponade

Effect of Macular Internal Limiting Membrane Peeling on Single Surgery Success Rates of Vitrectomy for Uncomplicated, Primary Macula-Off Retinal Detachment

Vitrectomy for the removal of idiopathic epiretinal membrane with or without internal limiting membrane peeling: a meta-analysis

Pars plana vitrectomy with and without peeling of the inner limiting membrane (ILM) for diabetic macular edema.

Re-operation of idiopathic full-thickness macular holes after initial surgery with internal limiting membrane peel.

Internal limiting membrane peeling versus no peeling for idiopathic full-thickness macular hole: a pragmatic randomized controlled trial.