NDLI: Flow Patterns and Wall Shear Stress Distributions at Atherosclerotic-Prone Sites in a Human Left Coronary Artery - An Exploration Using Combined Methods of CT and Computational Fluid Dynamics

Content Provider	IEEE Xplore Digital Library
Author	Suo Jin Yan Yang Oshinski, J. Tannenbaum, A. Gruden, J. Giddens, D.
Copyright Year	2004
Description	Author affiliation: Wallace H. Coulter Department of Biomedical Engineering, Georgia Tech and Emory University, Atlanta, GA (Suo Jin)
Abstract	Computed tomography (CT) slices are combined with computational fluid dynamics (CFD) to simulate the flow patterns in a human left coronary artery. The vascular model was reconstructed from CT slices scanned from a healthy volunteer in vivo. The spatial resolution of the slices is 0.6 × 0.6 × 0.625 mm so that geometrical details of the local wall surface of the vessel could be considered in the CFD modeling. This level of resolution is needed to investigate the wall shear stress (WSS) distribution, a factor generally recognized as a related to the atherogenesis. The WSS distributions on the main trunk and bifurcation of the left coronary artery of the model in one cardiac cycle are presented, and the results demonstrate that low and oscillating WSS is correlative with clinical observations of the atherosclerotic-prone sites in the left coronary artery.
Starting Page	3789
Ending Page	3791
File Size	777915
Page Count	3
File Format	PDF
ISBN	0780384393
DOI	10.1109/IEMBS.2004.1404062
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2004-09-01
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Stress Humans Arteries Computational fluid dynamics Computed tomography Spatial resolution Computational modeling In vivo Surface reconstruction Solid modeling WSS CFD coronary artery CT
Content Type	Text
Resource Type	Article

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Flow Patterns and Wall Shear Stress Distributions at Atherosclerotic-Prone Sites in a Human Left Coronary Artery - An Exploration Using Combined (2004)

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