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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Kim, C. Kang, E. Kim, Y.E. Lee, K.J. Kim, T.S. Kang, J.Y. |
| Copyright Year | 2009 |
| Description | Author affiliation: Nano-Bio research center, Korea Institute of Science and Technology, Seoul, KOREA (Kim, C.; Kang, E.; Kim, Y.E.; Kim, T.S.; Kang, J.Y.) || School of Mechanical Engineering, Korea University, Seoul, KOREA (Lee, K.J.) |
| Abstract | In this paper, we propose a microfluidic chip to generate well-defined microcapsule. In order to make core-shell microcapsule, a simple design capable of 3-dimensional hydrodynamic focusing was embedded in the proposed microfluidic chip. Cell suspension is focused 3-dimensional hydrodynamic in microchannel by the hillock based geometries, and then the core-shell structure of alginate microcapsules with thin membrane can be clearly identified. The mouse embryonic carcinoma cell line, P19, was cultured in the capsules and spherical EB (more than 70 %) with strong compaction was successfully formed within 2 days. |
| Starting Page | 2022 |
| Ending Page | 2025 |
| File Size | 1097493 |
| Page Count | 4 |
| File Format | |
| ISBN | 9781424441907 |
| e-ISBN | 9781424441938 |
| DOI | 10.1109/SENSOR.2009.5285660 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2009-06-21 |
| Publisher Place | USA |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Microfluidics Calcium Hydrodynamics Plasma properties Embryo Focusing Microchannel Geometry Mice Cells (biology) microfluidic microcapsule 3D hydrodynamic focusing |
| Content Type | Text |
| Resource Type | Article |
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