NDLI: A bio-inspired, chemo-responsive polymer nanocomposite for mechanically dynamic microsystems

Content Provider	IEEE Xplore Digital Library
Author	Hess, A. Dunning, J. Harris, J. Capadona, J.R. Shanmuganathan, K. Rowan, S.J. Weder, C. Tyler, D.J. Zorman, C.A.
Copyright Year	2009
Description	Author affiliation: Dept. of Macromolecular Science and Engineering, Case Western Reserve University, Cleveland, OH, USA (Shanmuganathan, K.; Rowan, S.J.; Weder, C.) \|\| Louis Stokes Cleveland VA Medical Center, OH, USA (Dunning, J.; Capadona, J.R.; Tyler, D.J.) \|\| Dept. of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA (Harris, J.) \|\| Dept. of Electrical Engineering and Computer Science, Case Western Reserve University, Cleveland, OH, USA (Hess, A.; Zorman, C.A.)
Abstract	This paper reports the development of a biologically-inspired, variable-modulus nanocomposite material for mechanically dynamic biomedical microsystems. This nanocomposite is comprised of a poly(vinyl acetate) matrix polymer that is reinforced with rigid cellulose nanofibers, and becomes very flexible when exposed to water. A direct-write CO laser was used to pattern structures in this chemical- and temperature-sensitive material. Tensile testing of laser-cut, micron-scale nanocomposite beams was performed using a custom-built tensile tester. These samples displayed a significant reduction in Young's modulus from 4.1 GPa to 6.1 MPa when the nanocomposite was exposed to phosphate buffered saline. Additionally, the modulus change was observed to be reversible upon drying of soaked tensile samples. As a well-suited application of this nanocomposite, cortical probes utilizing this material as a substrate were fabricated. Gold-coated, dual-shank cortical probes utilizing this nanocomposite as a substrate were shown to record action potentials from a single neuron in a cockroach brain.
Starting Page	224
Ending Page	227
File Size	566597
Page Count	4
File Format	PDF
ISBN	9781424441907
e-ISBN	9781424441938
DOI	10.1109/SENSOR.2009.5285522
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2009-06-21
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Polymers Nanobioscience Chemical lasers Biological materials Biomedical materials Optical materials Testing Probes Nanostructured materials Laser beams neural interfacing mechanically dynamic nanocomposite cortical probe
Content Type	Text
Resource Type	Article

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