NDLI: Rapid detection of progesterone by commercially available microelectrode chips

Content Provider	IEEE Xplore Digital Library
Author	Haochen Cui Cheng Cheng Wu, J. Eda, S.
Copyright Year	2013
Description	Author affiliation: Dept. of Forestry, Wildlife & Fisheries, Univ. of Tennessee, Knoxville, TN, USA (Eda, S.) \|\| Dept. of Electr. Eng. & Comput. Sci., Univ. of Tennessee, Knoxville, TN, USA (Haochen Cui; Cheng Cheng; Wu, J.)
Abstract	This work presents rapid detection of progesterone by utilizing a commercially available surface acoustic wave (SAW) resonator chip in coordination with an impedance affinity sensing method developed in our group. Interdigitated microelectrodes from the SAW chips were coated with anti-progesterone polyclonal antibody to capture progesterone and subsequently exposed to a solution containing progesterone. With the help of alternating current electrokinetics (ACEK) effects, binding of progesterone to the immobilized antibody was accelerated and, within two minutes, could be detected by continuous reading of the interfacial capacitance change over the microelectrodes. This ACEK-based capacitive sensor is of low cost, highly portable and easy to use, makes it perfect for point-of-care applications.
Starting Page	1
Ending Page	4
File Size	859482
Page Count	4
File Format	PDF
ISBN	9781467346429
ISSN	19300395
DOI	10.1109/ICSENS.2013.6688157
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2013-11-03
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Capacitance Surface impedance Surface treatment Microelectrodes Sensors Surface acoustic waves
Content Type	Text
Resource Type	Article
Subject	Electrical and Electronic Engineering

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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