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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Liu, J. Kuhn, H.G. Yujia Jing Dahlberg, J.-O. Ericsson, L. Nilsson, A. Nyberg, L. Ohady, B. Svensson, J. Carlberg, B. Cooper-Kuhn, C.M. Teng Wang Yihua Zhu |
| Copyright Year | 2009 |
| Description | Author affiliation: Key Laboratory of Ultrafine Materials to Ministry of Education, Department of Material Science and Engineering, East China University of Science and Technology, No 130, Meilong Road, Shanghai 200237, China (Yihua Zhu) || BioNano Systems Laboratory, Department of Microtechnology and Nanoscience Chalmers University of Technology, Göteborg, SE-412 96 (Sweden) (Liu, J.; Yujia Jing; Dahlberg, J.-O.; Ericsson, L.; Nilsson, A.; Nyberg, L.; Ohady, B.; Svensson, J.; Carlberg, B.; Teng Wang) || Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology Gothenburg University, Göteborg, SE-413 45 (Sweden) (Kuhn, H.G.; Cooper-Kuhn, C.M.) |
| Abstract | Stem cell growth and migration on nanofibrous scaffolds and micro-fluidic channels on Silicon-Chip were studied by using neural stem cells isolated from adult rats' brain. Electrospinning and lithographic technique were used for developing nanofibrous-polylactic acid (PLA) and polyurethane (PU) based-scaffolds and micro-fluidic channels on Si-Chips respectively. Immunocytochemical and morphological analysis showed better cell-matrix interaction with profound adhesion, proliferation and migration on the developed scaffolds. Cell culture assay with microfluidic channel revealed the ability of developed channel system in guiding neuronal stem cell growth towards specified directions. These studies extend the possibility of using developed nanofibrous scaffolds and micro-fluidic channel system for future electrical signal transmission based on living neural stem cells. |
| Starting Page | 1080 |
| Ending Page | 1085 |
| File Size | 2994946 |
| Page Count | 6 |
| File Format | |
| ISBN | 9781424444755 |
| ISSN | 05695503 |
| DOI | 10.1109/ECTC.2009.5074146 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2009-05-26 |
| Publisher Place | USA |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Stem cells Polymers Nanobioscience Medical treatment Biological materials Biodegradable materials Materials science and technology Electrochemical machining Programmable logic arrays Educational technology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Electronic, Optical and Magnetic Materials Electrical and Electronic Engineering |
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