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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Saha, Nayan Ranjan Sarkar, Gunjan Roy, Indranil Rana, Dipak Bhattacharyya, Amartya Adhikari, Arpita Mukhopadhyay, Asis Chattopadhyay, Dipankar |
| Description | Country affiliation: India Author Affiliation: Saha NR ( Department of Polymer Science and Technology, University of Calcutta, 92 A.P.C. Road, Kolkata 700009, India.); Sarkar G ( Department of Polymer Science and Technology, University of Calcutta, 92 A.P.C. Road, Kolkata 700009, India.); Roy I ( Department of Polymer Science and Technology, University of Calcutta, 92 A.P.C. Road, Kolkata 700009, India.); Rana D ( Department of Chemical and Biological Engineering, Industrial Membrane Research Institute, University of Ottawa, 161 Louis Pasteur St. , Ottawa, ON K1N 6N5, Canada.); Bhattacharyya A ( Department of Polymer Science and Technology, University of Calcutta, 92 A.P.C. Road, Kolkata 700009, India.); Adhikari A ( Department of Polymer Science and Technology, University of Calcutta, 92 A.P.C. Road, Kolkata 700009, India.); Mukhopadhyay A ( Department of Jute and Fiber Technology, Institute of Jute Technology, University of Calcutta, 35 Ballygunge Circular Road, Kolkata 700019, India.); Chattopadhyay D ( Department of Polymer Science and Technology, University of Calcutta, 92 A.P.C. Road, Kolkata 700009, India. Electronic address: dipankar.chattopadhyay@gmail.com.) |
| Abstract | Films based on methylcellulose (MC) and pectin (PEC) of different ratios were prepared. MC/PEC (90:10) (MP10) gave the best results in terms of mechanical properties. Sodium montmorillonite (MMT) (1, 3 and 5 wt%) was incorporated in the MP10 matrix. The resulting films were characterized by X-ray diffraction and transmission electron microscopy, and it was found that nanocomposites were intercalated in nature. Mechanical studies established that addition of 3 wt% MMT gave best results in terms of mechanical properties. However, thermo-gravimetric and dynamic mechanical analysis proved that decomposition and glass transition temperature increased with increasing MMT concentration from 1 to 5 wt%. It was also observed that moisture absorption and water vapor permeability studies gave best result in the case of 3 wt% MMT. Optical clarity of the nanocomposite films was not much affected with loading of MMT. In vitro drug release studies showed that MC/PEC/MMT based films can be used for controlled transdermal drug delivery applications. |
| File Format | HTM / HTML |
| ISSN | 01448617 |
| Volume Number | 136 |
| e-ISSN | 18791344 |
| Journal | Carbohydrate Polymers |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2016-01-20 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Biochemistry__semicolon__materials Discipline Science Bentonite Chemistry Drug Carriers Methylcellulose Nanocomposites Pectins Drug Liberation Humans Ketorolac Tromethamine Mechanical Phenomena Phase Transition Product Packaging Skin Solubility Solvents Volatilization Water Journal Article Research Support, Non-u.s. Gov't |
| Content Type | Text |
| Resource Type | Article |
| Subject | Organic Chemistry Materials Chemistry Polymers and Plastics |
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