NDLI: Monitoring of radiofrequency ablation with shear wave delay mapping

Content Provider	IEEE Xplore Digital Library
Author	Shi, W. Anand, A. Sethuraman, S. Sheng-Wen Huang Hua Xie Agarwal, H. Pingkun Yan Azevedo, J. Kruecker, J. Ng, G. Shamdasani, V. Pritchard, W. Karanian, J. Wood, B.
Copyright Year	2015
Description	Author affiliation: FDA, USA (Pritchard, W.; Karanian, J.) \|\| Philips Res. North America, Cambridge, MA, USA (Shi, W.; Anand, A.; Sethuraman, S.; Sheng-Wen Huang; Hua Xie; Agarwal, H.; Pingkun Yan; Azevedo, J.; Kruecker, J.) \|\| Philips Ultrasound, Bothell, WA, USA (Ng, G.; Shamdasani, V.) \|\| Nat. Inst. of Health, Bethesda, MD, USA (Wood, B.)
Abstract	Real-time monitoring of radiofrequency ablation is important to ensure adequate treatment coverage of liver tumors as well as protection of healthy tissues. The high stiffness contrast between ablated and non-treated tissues has led to the use of ultrasound elastography for coagulation zone visualization. A highly sensitive shear wave delay mapping approach was developed for ablation boundary detection, especially, in the presence of a rigid ablation needle. The shear wave technique was evaluated using ex-vivo bovine and porcine liver samples as well as whole livers from sedated live and fresh cadaver pigs. Initial tissue softening was seen ex-vivo for non-perfused livers, but not observed in-vivo for live livers with `cooling' blood perfusion. The lesion sizes (lateral radii) determined by the shear wave technique were generally in good agreement with those from gross pathology. In addition, T2-weighted MR images were acquired in 3D for direct assessments of ablated tissue volumes. Overall the shear wave technique appears feasible for defining and monitoring the progression of thermal lesion boundary.
Starting Page	1
Ending Page	4
File Size	985698
Page Count	4
File Format	PDF
e-ISBN	9781479981823
DOI	10.1109/ULTSYM.2015.0040
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2015-10-21
Publisher Place	Taiwan
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Liver Needles Ultrasonic imaging Lesions Imaging Bovine Real-time systems time-to-peak ablation monitoring radiofrequency ablation shear wave imaging stiffness elasticity
Content Type	Text
Resource Type	Article

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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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