NDLI: Prospective discrimination of vertebral fractures by axial transmission ultrasound using optimized first arriving signal velocity measurements

Content Provider	IEEE Xplore Digital Library
Author	Schneider, J. Raum, K. Pumberger, M. Zippelius, T. Hoff, E. Strube, P. Putzier, M. Minonzio, J.G. Laugier, P.
Copyright Year	2015
Description	Author affiliation: Lab. d'Imagerie Biomed., Sorbonne Univ., Paris, France (Minonzio, J.G.; Laugier, P.) \|\| Center for Musculoskeletal Surg., Charite-Universitatsmedizin Berlin, Berlin, Germany (Pumberger, M.; Zippelius, T.; Hoff, E.; Strube, P.; Putzier, M.) \|\| Berlin-Brandenburg Sch. for Regenerative Therapies, Charite-Universitatsmedizin Berlin, Berlin, Germany (Schneider, J.; Raum, K.)
Abstract	The objective of this study is to assess the clinical performance of a novel bi-directional axial transmission (BDAT) ultrasound prototype. The speed of sound of the first arriving signal $(V_{FAS})$ was measured at the radius (single site) and at the tibia (two sites) of 51 post-menopausal females. An optimized $V_{FAS}$ measurement protocol was introduced to reduce the clinical measurement time (from 30 to 10 minutes) by maintaining the robustness of the former method. The optimized protocol was efficient and showed excellent discrimination performance: the highest areas under the ROC curves (AUC) were found for $V_{FAS}$ radius (OR: 3.54; AUC: 0.81) and $V_{FAS}$ tibia medial surface (MS) (OR: 4.10; AUC: 0.81). Dual energy x-ray absorptiometry (DXA) at the lumbar spine exhibited similar fracture discrimination power (OR: 1.89; AUC: 0.81) compared to the ultrasonic method.
Starting Page	1
Ending Page	4
File Size	593767
Page Count	4
File Format	PDF
e-ISBN	9781479981823
DOI	10.1109/ULTSYM.2015.0513
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2015-10-21
Publisher Place	Taiwan
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Ultrasonic variables measurement Bones Ultrasonic imaging Acoustics Velocity measurement Bidirectional control osteoporosis axial transmission cortical bone first arriving signal
Content Type	Text
Resource Type	Article

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