NDLI: Wall Shear Rate method validation through multi-physics simulations

Content Provider	IEEE Xplore Digital Library
Author	Ricci, S. Swillens, A. Ramalli, A. Segers, P. Tortoli, P.
Copyright Year	2015
Description	Author affiliation: Dept. of Inf. Eng., Univ. of Florence, Florence, Italy (Ricci, S.; Ramalli, A.; Tortoli, P.) \|\| IBiTech-bioMMeda, Ghent Univ., Ghent, Belgium (Swillens, A.; Segers, P.)
Abstract	Wall Shear Stress (WSS), i.e. the tangential force that blood applies to the inner layer of the vessel wall, is associated with arterial remodeling and important cardiovascular diseases like the formation of atherosclerotic plaques. In simple, uniaxial flows, WSS can be derived as the blood viscosity multiplied by the Wall Shear Rate (WSR), i.e. the velocity gradient evaluated in the radial direction. The WSR is typically estimated by measuring the velocity of the blood in the vessel center and by assuming a parabolic velocity profile (Poiseuille model). Unfortunately, this model produces inaccurate results since it does not account for the complex flow configuration present in the vessel. In a different approach, the actual flow profile is measured instantaneously through a multigate technique, but the clutter corrupts the profile in proximity to the wall, i.e. where the WSR should be evaluated, so that the profile should be reconstructed. In this work, realistic multi-physics simulations of a patient-specific carotid bifurcation are used to assess the accuracy of a 2-step method for profile reconstruction and WSR measurement. The estimated WSR matches the model ground-truth with an accuracy of about 10%.
Starting Page	1
Ending Page	4
File Size	841083
Page Count	4
File Format	PDF
e-ISBN	9781479981823
DOI	10.1109/ULTSYM.2015.0331
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2015-10-21
Publisher Place	Taiwan
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Blood Doppler effect Accuracy Computational modeling Clutter Ultrasonic imaging Mathematical model Blood Velocity Profile Wall Shear Rate Multiphysics Simulations
Content Type	Text
Resource Type	Article

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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