NDLI: Feasibility of micro-elastography for tissue surrounding phase-change microbubbles using bubble wavelet transform

Content Provider	IEEE Xplore Digital Library
Author	Runna Liu Rui Huo Shanshan Xu Hong Hu Supin Wang Mingxi Wan
Copyright Year	2015
Description	Author affiliation: Dept. of Biomed. Eng., Xi'an Jiaotong Univ., Xi'an, China (Runna Liu; Rui Huo; Shanshan Xu; Hong Hu; Supin Wang; Mingxi Wan)
Abstract	Pathological states of soft tissue are usually correlated with changes in its mechanical properties. Currently, several sonoelastographic methods have been developed to evaluate the elastic properties. However, applicability of sonoelastography for small targets such as tissues surrounding tumor angiogenesis, is limited because of poor resolution and difficulty in producing detectable strain by external induction or internal physiological fluctuations. We propose to explore the possibility of quantifying the viscoelastic properties of soft tissues through phase-change microbubble (PCMB) dynamic in tissue and bubble wavelet transform detection method. A mother wavelet named “PCMB wavelet” was constructed according to the modified Yang-Church equation, and also expected to obtain a high correlation with echoes backscattered from the PCMBs. A transparent homogeneous tissue-mimicking polyacrylamide phantom containing nanoparticles of perfluoropentane was built. The comparison of contrast-to-tissue ratio among the images processed by continuous wavelet transform with “PCMB wavelet” of different shear elasticity and viscosity revealed the viscoelastic properties of the phantoms. The values of shear elasticity and viscosity of different kinds of phantoms were compared. This technique demonstrated the possibility to quantify the viscoelastic properties.
Starting Page	1
Ending Page	4
File Size	950213
Page Count	4
File Format	PDF
e-ISBN	9781479981823
DOI	10.1109/ULTSYM.2015.0290
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2015-10-21
Publisher Place	Taiwan
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Tumors Fluctuations Wavelet analysis Oscillators Phantoms Attenuation wavelet transform plane wave viscoelastic properties phase-change microbubbles
Content Type	Text
Resource Type	Article

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