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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Lan, X. Ye, L. He, M. Hu, Y. D. Lan, D. Zhu, Q. Feng, Z. Q. Zhang, L. Pu, H. B. Liu, Y. P. Huang, Q. K. |
| Description | Country affiliation: China Author Affiliation: Hu YD ( Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University Ya'an, Sichuan, China.); Huang QK ( Guangyuan Food of Animal Husbandry Bureau, Guanyuan, Sichuan, China.); Zhu Q ( Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University Ya'an, Sichuan, China.); Lan D ( Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University Ya'an, Sichuan, China.); Feng ZQ ( Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University Ya'an, Sichuan, China.); Zhang L ( Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University Ya'an, Sichuan, China.); Lan X ( Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University Ya'an, Sichuan, China.); Ye L ( Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University Ya'an, Sichuan, China.); Liu YP ( Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University Ya'an, Sichuan, China liuyp578@163.com.); He M ( Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University Ya'an, Sichuan, China.); Pu HB ( Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University Ya'an, Sichuan, China.) |
| Abstract | Gonadotropin-inhibitory hormone (GnIH) gene is an important gene in reproduction. In this study, we screened single-nucleotide polymorphisms (SNPs) in the chicken GnIH gene among 204 individuals in Erlang mountainous chickens. We then analyzed the associations between polymorphisms of the GnIH gene and 5 egg production traits in chickens. Five SNPs (T3305C, T3310C, G3403C, G3411A, and T3591C) were detected. Associations between polymorphic loci and age at first egg, body weight at first egg, weight at first egg, egg weight in 300 days, and egg production in 300 days were analyzed using analysis of covariance. The results showed that SNP1, SNP3, and SNP4 had large effects on age at first egg, while SNP5 had a large effect on body weight at first egg; of the effect of the TT genotype was significantly higher than that of CT (P < 0.01). Further analysis show that the highest frequency (0.2353) haplotype H1H1 was associated with the latest age at first egg. The H4H5 haplotype had a positive effect on egg production in 300 days and a negative effect on weight at first egg. We observed no association between the H3H3 haplotype and body weight at first egg. |
| e-ISSN | 16765680 |
| Journal | Genetics and Molecular Research |
| Issue Number | 1 |
| Volume Number | 14 |
| Language | English |
| Publisher | Fundação de Pesquisas Científicas de Ribeirão Preto |
| Publisher Date | 2015-01-23 |
| Publisher Place | Brazil |
| Access Restriction | Open |
| Subject Keyword | Avian Proteins Genetics Genetic Association Studies Polymorphism, Single Nucleotide Alleles Animals Gene Frequency Genotype Haplotypes Linkage Disequilibrium Sequence Analysis, Dna Research Support, Non-u.s. Gov't Discipline Genetics Discipline Molecular Biology Discipline Bioinformatics |
| Content Type | Text |
| Resource Type | Article |
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