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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Park, Juhun Park, Tai Hyun Hong, Seunghun Lee, Seung Hwan Lim, Jong Hyun |
| Description | Author Affiliation: Lee SH ( School of Chemical and Biological Engineering, Seoul National University, Seoul 151-742, Republic of Korea.); Lim JH ( School of Chemical and Biological Engineering, Seoul National University, Seoul 151-742, Republic of Korea.); Park J ( Department of Physics and Astronomy, Seoul National University, Seoul 151-742, Republic of Korea.); Hong S ( Department of Physics and Astronomy, Seoul National University, Seoul 151-742, Republic of Korea); Park TH ( School of Chemical and Biological Engineering, Seoul National University, Seoul 151-742, Republic of Korea) |
| Abstract | A bioelectronic nose based on a novel microfluidic system (µBN) was fabricated to detect gaseous trimethylamine (TMA) in real-time. Single-walled carbon nanotube-field effect transistors (SWNT-FETs) were functionalized with olfactory receptor-derived peptides (ORPs) that can recognize the TMA molecules. The ORP-coated SWNT-FETs were assembled with a microfluidic channel and were sealed with top and bottom frames. This simple process was used to complete the µBNs, and a well-defined condition was achieved to detect the gaseous molecules. The µBNs allowed us to detect gaseous TMA molecules down to 10 parts per trillion (ppt) in real-time and showed high selectivity when distinguishing gaseous TMA from other gaseous odorants. The sensor was used to determine the quality of seafood (oysters), and spoiled seafood and other types of spoiled foods were also successfully discriminated without any pretreatment processes. These results indicate that portable-scale platforms can be manufactured by using µBNs and can be applicable for real-time on-site gas analysis. |
| ISSN | 09565663 |
| Volume Number | 71 |
| e-ISSN | 18734235 |
| Journal | Biosensors and Bioelectronics |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2015-09-15 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Biosensing Techniques Instrumentation Food Analysis Gases Analysis Methylamines Microfluidics Seafood Amino Acid Sequence Animals Equipment Design Food Quality Metabolism Immobilized Proteins Chemistry Limit Of Detection Molecular Sequence Data Nanotubes, Carbon Peptides Receptors, Odorant Transistors, Electronic Evaluation Studies Journal Article Research Support, Non-u.s. Gov't Discipline Biotechnology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Nanoscience and Nanotechnology Medicine Biophysics Biomedical Engineering Biotechnology Electrochemistry |
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