NDLI: Integration of SBML models for the description of biological system in a lab-on-chip

Content Provider	IEEE Xplore Digital Library
Author	Rezgui, A. Madec, M. Lallement, C. Haiech, J.
Copyright Year	2015
Description	Author affiliation: Comput. Sci. & Imaging Lab. - ICube Lab., Strasbourg Univ., Illkirch, France (Rezgui, A.; Madec, M.; Lallement, C.) \|\| Therapeutic Innovations Lab. (LIT), Strasbourg Univ., Illkirch, France (Haiech, J.)
Abstract	Lab-on-chips (LOCs) are small systems, which integrate, in the same device, several functions involving chemical analysis with bio-processing functionalities typically performed in a laboratory. As a consequence, it is a multi-domain system that can be described and designed with VHDL-AMS, a hardware description language that natively supports electronics, thermics and fluidics. On the other hand, the biological part of the LOC is often modeled and simulated with languages suitable to the field of biology. One of the most commonly used ones is SBML (System Biology Markup Language). To promote the integration of biological parts of the LOCs in the VHDL-AMS environment, we have developed software that automatically generates the VHDL-AMS models from SBML descriptions. The potential of this tool is illustrated in the context of the design of the lab-on-chip suitable for the detection of micro-pollutants in drinking water.
Starting Page	165
Ending Page	170
File Size	477788
Page Count	6
File Format	PDF
e-ISBN	9788363578077
DOI	10.1109/MIXDES.2015.7208504
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2015-06-25
Publisher Place	Poland
Access Restriction	Subscribed
Rights Holder	Department of Microelectronics and Computer Science, Lodz Univeristy of Technology
Subject Keyword	Solid modeling Lab-On-Chip modeling Biological system modeling simulation VHDL-AMS SBML Biochemistry Biological information theory Biological and Biochemical network translation Tool Kinetic theory Mathematical model
Content Type	Text
Resource Type	Article

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