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| Content Provider | IEEE Xplore Digital Library |
|---|---|
| Author | Jun Li Arumugam, P.U. Chen, H. Cassell, A. |
| Copyright Year | 2008 |
| Description | Author affiliation: Dept. of Chem., Kansas State Univ., Manhattan, KS (Jun Li) |
| Abstract | Dielectrophoresis (DEP) is an effective microelectronic technique for trapping and manipulating biological particles in a microfluidic environment, which relies on the highly asymmetric electric field gradient created by the microelectrodes. Here we demonstrate an AC DEP technique for single-bacteria trapping using nanoelectrode arrays (NEAs) in a "points-and-lid" configuration. The NEA is based on vertically aligned carbon nanofibers (CNFs) embedded in $SiO_{2}$ matrix. The miniaturization of the electrode size provides a highly focused electric field with the gradient enhanced by several orders of magnitude. Finite element modeling indicated that the pDEP force using such NEA-based devices can be increased by over 100 times. Experiments indicated that the bacteria can be trapped instantaneously on to the exposed CNF tip with an AC voltage of ~3 $V_{pp}.$ In most cases, a single E. coli bacterium is trapped at a single CNF site due to the screening effect. Such nano-DEP device allows the integration of millions of nanolectrodes deterministically in lab-on-a-chip devices that can be used for effective cell manipulating and concentration. |
| Starting Page | 826 |
| Ending Page | 827 |
| File Size | 493322 |
| Page Count | 2 |
| File Format | |
| ISBN | 9781424421039 |
| DOI | 10.1109/NANO.2008.246 |
| Language | English |
| Publisher | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Publisher Date | 2008-08-18 |
| Publisher Place | USA |
| Access Restriction | Subscribed |
| Rights Holder | Institute of Electrical and Electronics Engineers, Inc. (IEEE) |
| Subject Keyword | Arrays Nanobioscience Charge carrier processes Electrodes Microorganisms Force Microfluidics |
| Content Type | Text |
| Resource Type | Article |
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