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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Zhou, Yanmei Wang, Enze Pang, Lanfang Zhang, Junli Pang, Xiaobin Yu, Fang Qiao, Han |
| Description | Author Affiliation: Wang E ( Institute of Environmental and Analytical Sciences, College of Chemistry and Chemical Engineering, Henan University, Kaifeng, Henan 475004, PR China.); Pang L ( Institute of Environmental and Analytical Sciences, College of Chemistry and Chemical Engineering, Henan University, Kaifeng, Henan 475004, PR China.); Zhou Y ( Institute of Environmental and Analytical Sciences, College of Chemistry and Chemical Engineering, Henan University, Kaifeng, Henan 475004, PR China. Electronic address: zhouyanmei@henu.edu.cn.); Zhang J ( Key Laboratory of Plant Stress Biology, Henan University, Kaifeng 475004, PR China.); Yu F ( Institute of Environmental and Analytical Sciences, College of Chemistry and Chemical Engineering, Henan University, Kaifeng, Henan 475004, PR China.); Qiao H ( Institute of Environmental and Analytical Sciences, College of Chemistry and Chemical Engineering, Henan University, Kaifeng, Henan 475004, PR China.); Pang X ( Pharmaceutical Institute, Henan University, Kaifeng 475004, PR China.) |
| Abstract | We designed and synthesized a mono-Schiff-base fluorescent probe (Probe 1) based on a boron-dipyrromethene (BODIPY) dye. By investigating the recognition of Au(3+) through an irreversible C=N bond hydrolysis reaction, Probe 1 exhibited higher properties such as acting as a 'naked eye' probe, stability to pH, fast-response of 90s, a lower detection limit of 60 nM, stronger antijamming capability, and better live-cells imaging with low cytotoxicity compared with other probes. Even in relatively high temperatures, Probe 1 maintained its own excellent characteristic. More importantly, this is the first time that one chemosensor could be successfully applied to Au(3+) imaging in zebrafish, which demonstrated the performance that Probe 1 exhibited wonderful organism permeability. |
| ISSN | 09565663 |
| Volume Number | 77 |
| e-ISSN | 18734235 |
| Journal | Biosensors and Bioelectronics |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2016-03-15 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Boron Compounds Chemistry Fluorescent Dyes Chemical Synthesis Gold Metabolism Microscopy, Fluorescence Methods Schiff Bases Zebrafish Animals Reproducibility Of Results Sensitivity And Specificity Tissue Distribution Whole Body Imaging Journal Article Research Support, Non-u.s. Gov't Discipline Biotechnology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Nanoscience and Nanotechnology Medicine Biophysics Biomedical Engineering Biotechnology Electrochemistry |
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