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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Takhar, Arunjit Singh Sharma, Anup Ney, Alex Patel, Meera |
| Description | Author Affiliation: Takhar AS ( Department of Breast & General Surgery, St George's Healthcare National Health Service Trust, London, UK.) |
| Abstract | We report the case of a 53-year-old lady who presented with a lump in her left breast. Her initial investigations demonstrated a grade III invasive ductal carcinoma of the breast that was tethered to the pectoralis major; imaging and cytology also revealed metastatic nodes in the left axilla. After undergoing neoadjuvant chemotherapy with evidence of clinical and radiological tumour response, a wire-guided wide local excision and axillary node clearance was performed. When a histological analysis of the specimen was performed, there was no evidence of a viable metastatic tumour in the axillary lymph nodes, but there were several areas of extramedullary haematopoiesis. There are only two other reports in the literature of this finding. This could represent a potential source of false-positive diagnosis of axillary metastasis from breast cancer. It would be prudent to consider biopsy prior to clearance if there are megakaryocytes in axillary node cytology. |
| e-ISSN | 1757790X |
| Journal | BMJ Case Reports |
| Volume Number | 2013 |
| Language | English |
| Publisher | BMJ Publishing Group Ltd. |
| Publisher Place | Great Britain (UK) |
| Access Restriction | Open |
| Subject Keyword | Antineoplastic Agents Therapeutic Use Breast Neoplasms Pathology Carcinoma, Ductal, Breast Hematopoiesis, Extramedullary Lymph Nodes Lymphatic Metastasis Diagnosis Megakaryocytes Axilla Surgery Biopsy Drug Therapy Chemotherapy, Adjuvant Cytodiagnosis Lymph Node Excision Neoadjuvant Therapy Neoplasm Staging Multidisciplinary |
| Content Type | Text |
| Resource Type | Article |
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