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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Jha, Praveen Jain, Nirdesh Singh, Ajay Kumar Himanshu, D. |
| Description | Author Affiliation: Jha P ( Department of Internal Medicine, KGMU., Gwalior, Madhya Pradesh, India.) |
| Abstract | Imatinib mesylate is a tyrosine kinase inhibitor used widely as the first-line treatment for chronic myeloid leukaemia (CML). The side-effect profile of this drug includes fluid retention, muscle cramps, diarrhoea, myelosuppression and skin rashes. Of these, rashes of the type maculo-papular eruptions and oedema developed most commonly. The cutaneous adverse reactions other than maculo-papular eruptions are rare with imatinib. Severe and life-threatening cutaneous reactions can occur in 5% cases. Here, the author reports a case of newly diagnosed CML that developed Steven-Johnsons syndrome due to imatinib therapy. Patient responded and discharged successfully on withdrawal of the culminating drug. |
| e-ISSN | 1757790X |
| Journal | BMJ Case Reports |
| Volume Number | 2013 |
| Language | English |
| Publisher | BMJ Publishing Group Ltd. |
| Publisher Place | Great Britain (UK) |
| Access Restriction | Open |
| Subject Keyword | Benzamides Adverse Effects Leukemia, Myelogenous, Chronic, BCR-ABL Positive Drug Therapy Piperazines Pyrimidines Stevens-Johnson Syndrome Chemically Induced Antineoplastic Agents Therapeutic Use Biopsy Diagnosis, Differential Imatinib Mesylate Protein-Tyrosine Kinases Antagonists & Inhibitors Diagnosis Multidisciplinary |
| Content Type | Text |
| Resource Type | Article |
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