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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Nijhawan, Raje Katoch, Deeksha Bansal, Reema Gupta, Amod |
| Description | Author Affiliation: Katoch D ( Department of Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India.) |
| Abstract | A 49-year-old woman had blurred vision and floaters of 4 days duration in the right eye. Ocular examination revealed granulomatous panuveitis, vitritis and diffuse retinal vasculitis. Following a strongly positive tuberculin skin test, she received antitubercular therapy with oral steroids and immunosuppressants. A year later, despite therapy, vitritis and vasculitis persisted. Additionally, yellowish white lesions appeared beneath the retinal pigment epithelium. Fluorescein angiography revealed a leopard skin appearance. Following a negative vitreous biopsy, she was subjected to a chorioretinal biopsy which revealed non-Hodgkin's lymphoma. MRI was normal. The ocular lesions resolved following intravitreal methotrexate injections. MRI of the brain was repeated every 3 months to rule out central nervous system (CNS) involvement. About 2.5 years after initial presentation, she complained of ataxia, hypersomnia and speech difficulty. MRI of the brain now showed lesions in the thalamocapsular region and the corpus callosum splenium suggestive of CNS lymphoma. She underwent a whole brain radiation with symptomatic improvement followed by chemotherapy. |
| e-ISSN | 1757790X |
| Journal | BMJ Case Reports |
| Volume Number | 2013 |
| Language | English |
| Publisher | BMJ Publishing Group Ltd. |
| Publisher Place | Great Britain (UK) |
| Access Restriction | Open |
| Subject Keyword | Central Nervous System Neoplasms Diagnosis Eye Neoplasms Lymphoma, Non-Hodgkin Retinal Vasculitis Angiography Drug Therapy Radiotherapy Combined Modality Therapy Diagnosis, Differential Magnetic Resonance Imaging Surgery Multidisciplinary |
| Content Type | Text |
| Resource Type | Article |
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