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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Sangwan, Virender S. Bhalekar, Swapnil Lal, Ikeda Basu, Sayan |
| Description | Author Affiliation: Bhalekar S ( Cornea and Anterior Segment Services, L V Prasad Eye Institute, Hyderabad, Andhra Pradesh, India.) |
| Abstract | A 3-year-old child sustained severe ocular surface burns in her left eye after accidental lime injury. Despite appropriate management in the acute stage, she developed limbal stem cell deficiency (LSCD) in that eye. This was initially treated with autologous ex vivo cultivated limbal epithelial transplantation (CLET), which unfortunately failed after 6 months resulting in recurrence of LSCD. One year following CLET, she underwent simple limbal epithelial transplantation (SLET) using autologous donor tissue from the healthy fellow eye. Successful restoration of the ocular surface following SLET combined with amblyopia therapy led to significant cosmetic and functional improvement. One year following SLET her vision in the left eye was 20/80 and she continues to maintain a stable, avascular and completely epithelised corneal surface. This case illustrates that SLET is effective in treating LSCD even in cases that are conventionally considered to be at high risk for failure of limbal stem cell transplantation. |
| e-ISSN | 1757790X |
| Journal | BMJ Case Reports |
| Volume Number | 2013 |
| Language | English |
| Publisher | BMJ Publishing Group Ltd. |
| Publisher Place | Great Britain (UK) |
| Access Restriction | Open |
| Subject Keyword | Burns, Chemical Surgery Corneal Diseases Epithelium, Corneal Eye Burns Limbus Corneae Stem Cell Transplantation Transplantation, Autologous Amblyopia Etiology Therapy Child, Preschool Corneal Transplantation Cytology Injuries Stem Cells Vision, Ocular Multidisciplinary |
| Content Type | Text |
| Resource Type | Article |
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