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| Content Provider | PubMed Central |
|---|---|
| Author | Song, Juhyun Lee, Won Taek Park, Kyung Ah Lee, Jong Eun |
| Copyright Year | 2014 |
| Abstract | Vascular dementia is caused by various factors, including increased age, diabetes, hypertension, atherosclerosis, and stroke. Adiponectin is an adipokine secreted by adipose tissue. Adiponectin is widely known as a regulating factor related to cardiovascular disease and diabetes. Adiponectin plasma levels decrease with age. Decreased adiponectin increases the risk of cardiovascular disease and diabetes. Adiponectin improves hypertension and atherosclerosis by acting as a vasodilator and antiatherogenic factor. Moreover, adiponectin is involved in cognitive dysfunction via modulation of insulin signal transduction in the brain. Case-control studies demonstrate the association between low adiponectin and increased risk of stroke, hypertension, and diabetes. This review summarizes the recent findings on the association between risk factors for vascular dementia and adiponectin. To emphasize this relationship, we will discuss the importance of research regarding the role of adiponectin in vascular dementia. |
| Related Links | http://dx.doi.org/10.1155/2014/261672 |
| Starting Page | 261672 |
| File Format | |
| ISSN | 23146133 |
| e-ISSN | 23146141 |
| Journal | BioMed Research International |
| Volume Number | 2014 |
| Language | English |
| Publisher | Hindawi Publishing Corporation |
| Publisher Date | 2014-01-01 |
| Access Restriction | Open |
| Rights Holder | Hindawi Publishing Corporation |
| Subject Keyword | Research in Higher Education |
| Content Type | Text |
| Resource Type | Article |
| Subject | Immunology and Microbiology Medicine Biochemistry, Genetics and Molecular Biology |
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