NDLI: Using myocardium-to-background ratio to get the optimal starting angle for a non-360-degree upright cardiac SPECT acquisition

Content Provider	IEEE Xplore Digital Library
Author	Babla, H. Chuanyong Bai Conwell, R.L. Old, R.N.
Copyright Year	2011
Description	Author affiliation: Digirad Corporation, 13950 Stowe Drive, Poway, CA 92064, USA (Babla, H.; Chuanyong Bai; Conwell, R.L.; Old, R.N.)
Abstract	Background: Myocardium counts in the projection data and myocardium wall ratios in the reconstructed images have been used to find the optimal angular sampling for 180° supine SPECT imaging. However, supine and upright images demonstrate different soft tissue attenuation patterns. In this work, we propose the use of myocardium-to-background ratio (MBR) in the projection data as a figure-of-merit to determine the optimal starting angle for upright cardiac SPECT imaging. We hypothesize that higher MBR in the projection data means better signal-to-noise ratio and leads to better quality reconstructed images. Methods: We performed MBR analysis for 76 patient images (38 stress-rest studies) acquired with upright SPECT camera. Out of the 76, 22 were acquired with starting angle of right anterior oblique (RAO) 45° in 180°, 26 with RAO 30° in 180° and 22 with RAO 38° in 202°. We separated the male (34) and female (42) data and compared the MBR at each projection angle. For the MBR analysis, the myocardium wall and the background in each projection were identified in four steps: (1) a volume image was reconstructed using FBP algorithm, (2) left ventricle was segmented from the volume image, (3) the segmented image was reprojected to obtain the region of interest (ROI) to calculate the average counts in the myocardium, and (4) the ROI in step (3) was blurred then subtracted by the ROI in step (3) to derive the ROI to calculate background counts. Results: MBR reached a local peak at RAO 30° for all the data. For males, the MBR at RAO 45° and RAO 38° was lower than RAO 30° but higher than left posterior oblique (LPO) 60° (towards the end of the acquisition). For females, the MBR at RAO 38° and RAO 45° was lower than RAO 30° and LPO 60°. Conclusions: Using MBR as the figure of merit, we conclude that for males, starting angle of RAO 38° or RAO 45° is preferred over RAO 30° for upright cardiac SPECT imaging. For females, however, starting angle of RAO 30° is preferred.
Starting Page	2760
Ending Page	2762
File Size	692749
Page Count	3
File Format	PDF
ISBN	9781467301183
ISSN	10823654
e-ISBN	9781467301206
DOI	10.1109/NSSMIC.2011.6152964
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2011-10-23
Publisher Place	Spain
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Single photon emission computed tomography Lead Heating Myocardium Upright imaging Myocardium-to-background ratio Myocardial Perfusion SPECT Optimal starting angle
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
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7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
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9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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