NDLI: Generation and evaluation of a simultaneous cardiac and respiratory gated Rb-82 PET simulation

Content Provider	IEEE Xplore Digital Library
Author	Min Jae Park Si Chen Taek-Soo Lee Fung, G.S.K. Lodge, M. Tsui, B.M.W.
Copyright Year	2011
Description	Author affiliation: Division of Medical Imaging Physics, Department of Radiology, Johns Hopkins University, Baltimore, MD 21287 USA (Min Jae Park; Si Chen; Taek-Soo Lee; Fung, G.S.K.; Tsui, B.M.W.) \|\| Department of Radiology, Johns Hopkins University, Baltimore, MD 21287 USA (Lodge, M.)
Abstract	The goal is to generate and evaluate a simulated 4D Rb-82 PET dataset that realistically models simultaneous respiratory and cardiac motions for use to study the effects of the motions and their compensation using various gating schemes. Normal cardiac and respiratory (C&R) motions were simulated separately using the realistic 4D XCAT phantoms. The C&R motion cycles were divided into 24 and 48 equally-spaced time points, respectively. The simultaneous dual motions were modeled by 24×48 phantoms with different combinations of C&R motion phases. Almost noise-free projections of the heart, blood pool, lungs, liver, stomach, spleen, and the remaining body were simulated separately using the combined SimSET and GATE Monte Carlo simulation program which is 12 times faster than GATE alone. The projections were scaled and combined to simulate a typical Rb-82 myocardial perfusion (MP) PET patient study. The no gating, 6-frame respiratory gating only, 8-frame cardiac gating only, and simultaneous 6-frame respiratory and 8-frame cardiac gating schemes were applied. Each gated projection dataset was reconstructed using a 2D OS-EM without and with attenuation correction (AC) using an averaged and gated attenuation maps. The reconstructed images were evaluated in terms of artifactual non-uniformity in the MP polar map. Significant artifactual non-uniformity was found in the MP polar map over all gating scheme without AC. With AC, the artifactual decreases in both the anterior and inferior regions were reduced with respiratory gating. Cardiac motion alone did not cause significant artifactual non-uniformity. In addition, the combination of dual gating and AC using the gated attenuation map provided the most uniform MP polar map. We demonstrated the flexibility and utility of the 4D XCAT phantom set with simultaneous C&R motions. It is a powerful tool to study motion effects on MP PET studies and to evaluate C&R gating schemes, AC and quantitative 4D PET image reconstruction methods.
Starting Page	3327
Ending Page	3330
File Size	1268573
Page Count	4
File Format	PDF
ISBN	9781467301183
ISSN	10823654
e-ISBN	9781467301206
DOI	10.1109/NSSMIC.2011.6152601
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2011-10-23
Publisher Place	Spain
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Logic gates Positron emission tomography Argon Attenuation Phantoms Single photon emission computed tomography
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Registration between respiratory-gated PET/CT and high-resolution CT with XCAT simulations: Evaluation and optimization for subsequent PVC

4D respiratory motion-corrected Rb-82 myocardial perfusion PET image reconstruction

Generation and Evaluation of a Simultaneous Cardiac and Respiratory Gated Rb-82 PET Simulation

Statistical motion modeling of the thorax applied to respiratory gated FDG PET

Simultaneous Attenuation and Scatter Corrections in Small Animal PET Imaging

Joint registration of attenuation and activity images in gated TOF-PET

A 5D anthropomorphic numerical phantom for respiratory-gated parametric imaging simulation studies in dynamic emission tomography

Motion Correction and Attenuation Correction for Respiratory Gated PET Images

Performance evaluation of 4D reconstruction methods for gated cardiac single photon emission computed tomography in obese patients

Generation and evaluation of a simultaneous cardiac and respiratory gated Rb-82 PET simulation

Similar Documents

Registration between respiratory-gated PET/CT and high-resolution CT with XCAT simulations: Evaluation and optimization for subsequent PVC

4D respiratory motion-corrected Rb-82 myocardial perfusion PET image reconstruction

Generation and Evaluation of a Simultaneous Cardiac and Respiratory Gated Rb-82 PET Simulation

Statistical motion modeling of the thorax applied to respiratory gated FDG PET

Simultaneous Attenuation and Scatter Corrections in Small Animal PET Imaging

Joint registration of attenuation and activity images in gated TOF-PET

A 5D anthropomorphic numerical phantom for respiratory-gated parametric imaging simulation studies in dynamic emission tomography

Motion Correction and Attenuation Correction for Respiratory Gated PET Images

Performance evaluation of 4D reconstruction methods for gated cardiac single photon emission computed tomography in obese patients

Generation and evaluation of a simultaneous cardiac and respiratory gated Rb-82 PET simulation