NDLI: Small-field angiographic imaging of tumor blood vessels in rabbit auricle using X-ray SATICON camera and synchrotron radiation

Content Provider	IEEE Xplore Digital Library
Author	Umetani, K. Yamashita, T. Maehara, N. Tokiya, R. Imai, S. Kajihara, Y.
Copyright Year	2003
Description	Author affiliation: Life & Environ. Sci. Div., Japan Synchrotron Radiat. Res. Inst., Hyogo, Japan (Umetani, K.)
Abstract	Microangiography with spatial resolution in the micrometer range was carried out for depicting angiogenic vessels in a rabbit model of cancer using a high-resolution detector and a third generation synchrotron radiation source at SPring-8. The long source-to-object distance and small source spot of synchrotron radiation radiography are able to produce high-resolution images. The imaging system was composed of an X-ray direct-conversion type detector incorporating an X-ray SATlCON pickup tube. Microangiographic images were obtained with no geometric blur and were stored in a digital frame memory system with a 1024 /spl times/ 1024-pixel, 10-bit format. A VX2 carcinoma was transplanted into a rabbit auricle. At seven days after transplantation, small tumor blood vessels with diameters of 10-30 /spl mu/m in an immature vascular network produced by angiogenesis were observed using monochromatic X-rays after contrast agent injection to the auricular artery.
Sponsorship	Whitaker Found
Starting Page	978
Ending Page	981
File Size	823456
Page Count	4
File Format	PDF
ISBN	0780377893
ISSN	1094687X
DOI	10.1109/IEMBS.2003.1279931
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2003-09-17
Publisher Place	Mexico
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Optical imaging Neoplasms Blood vessels Biomedical imaging Rabbits X-ray imaging Cameras Synchrotron radiation High-resolution imaging Spatial resolution
Content Type	Text
Resource Type	Article

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