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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Wang, Panpan Yu, Jinghua Zhu, Peihua Zhang, Yan Sun, Guoqiang Kan, Lingling |
| Description | Country affiliation: China Author Affiliation: Zhu P ( Key Laboratory of Chemical Sensing & Analysis in University of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, China.); Wang P ( Key Laboratory of Chemical Sensing & Analysis in University of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, China.); Kan L ( Key Laboratory of Chemical Sensing & Analysis in University of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, China.); Sun G ( Key Laboratory of Chemical Sensing & Analysis in University of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, China.); Zhang Y ( Key Laboratory of Chemical Sensing & Analysis in University of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, China.); Yu J ( Key Laboratory of Chemical Sensing & Analysis in University of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, China. Electronic address: ujn.yujh@gmail.com.) |
| Abstract | A novel self-assemble approach was developed for constructing a linear bicontinuous donor-acceptor, (H2BCPP)n-C60, arrays on indium-tin oxide electrode. Electronic absorption spectra, fluorescence spectra and atomic force microscopy were used as powerful tools to characterize H2BCPP, (H2BCPP)n arrays and (H2BCPP)n-C60 arrays. The (H2BCPP)n-C60 arrays enhanced the photocurrent generation capability, and presented an efficient photoelectrochemical immunosensing platform for the ultrasensitive detection of carcinoembryonic antigen (CEA). The quantitative measurement of CEA was based on the decrease in the photocurrent intensity of the (H2BCPP)n-C60 arrays, which was resulted from the competition between CEA and CEA-CdTe. A linear relationship between the photocurrent decrease and the CEA concentration was obtained in the wide range from 0.01 to 60 ng mL(-1) with a detection limit of 3.4 pg mL(-1). The proposed sensor showed high sensitivity, stability and reproducibility, and provided a promising platform for other biomolecular detection. |
| ISSN | 09565663 |
| Journal | Biosensors and Bioelectronics |
| Volume Number | 68 |
| e-ISSN | 18734235 |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2015-06-15 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Biosensing Techniques Carcinoembryonic Antigen Isolation & Purification Microscopy, Atomic Force Journal Article Research Support, Non-u.s. Gov't Discipline Biotechnology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Nanoscience and Nanotechnology Medicine Biophysics Biomedical Engineering Biotechnology Electrochemistry |
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