Please wait, while we are loading the content...
Please wait, while we are loading the content...
| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Yuan, Yali Wang, Haijun Chai, Yaqin Yuan, Ruo |
| Description | Author Affiliation: Wang H ( Key Laboratory of Luminescent and Real-Time Analytical Chemistry, Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, People's Republic of China.); Yuan Y ( Key Laboratory of Luminescent and Real-Time Analytical Chemistry, Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, People's Republic of China.); Chai Y ( Key Laboratory of Luminescent and Real-Time Analytical Chemistry, Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, People's Republic of China. Electronic address: yqchai@swu.edu.cn.); Yuan R ( Key Laboratory of Luminescent and Real-Time Analytical Chemistry, Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, People's Republic of China. Electronic address: yuanruo@swu.edu.cn.) |
| Abstract | Co-reactant electrochemiluminescence (ECL) is a simple and effective method for sensitive detection with amplified ECL signals. However, the intermolecular interaction between the luminescent reagents and their corresponding co-reactants, which is widely applied, has disadvantages in poor stability, low efficiency of electron transfer and relatively high loss of energy. In this work, an intramolecular self-enhanced ECL is proposed to settle this problem. Firstly, palladium nanowires (PdNWs) are synthesized with a green procedure in which Lentinan (LNT), one of ß-glucans with a triple helical conformation (t-LNT) in aqueous solution and single chains (s-LNT) at a temperature higher than 130°C, is used as stabilizer and reducing agent. The abtined PdNWs are applied to immobilize polyamidoamine (PAMAM) dendrimer which further reacts with tris (4, 4'-dicarboxylicacid-2, 2'-bipyridyl) ruthenium (II) dichloride to form a new electrochemiluminescent derivative (PdNWs-PAMAM-Ru). In this way, the Ru (II) luminophore and its co-reactive groups (amine groups in PAMAM) exist in the same complex, by which the electronic transmission distance is shortened and the luminous properties including stability and efficiency are enhanced. Moreover, due to the high specific surface areas and good electro-catalytic ability of PdNWs, the obtained PdNWs-PAMAM-Ru can be also applied to immobilize detection antibody (Ab2). Then, a sandwiched and sensitive ECL immunosensor is fabricated for the detection of carcinoembryonic antigen (CEA) with a wide linear ranged from 0.001 ng mL(-1) to 80 ng mL(-1) and a low detection limit of 0.3 pg mL(-1). |
| ISSN | 09565663 |
| Volume Number | 68 |
| e-ISSN | 18734235 |
| Journal | Biosensors and Bioelectronics |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2015-06-15 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Biosensing Techniques Carcinoembryonic Antigen Isolation & Purification Nanowires Chemistry Dendrimers Gold Humans Lentinan Chemical Synthesis Limit Of Detection Metal Nanoparticles Palladium Ruthenium Beta-glucans Journal Article Discipline Biotechnology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Nanoscience and Nanotechnology Medicine Biophysics Biomedical Engineering Biotechnology Electrochemistry |
National Digital Library of India (NDLI) is a virtual repository of learning resources which is not just a repository with search/browse facilities but provides a host of services for the learner community. It is sponsored and mentored by Ministry of Education, Government of India, through its National Mission on Education through Information and Communication Technology (NMEICT). Filtered and federated searching is employed to facilitate focused searching so that learners can find the right resource with least effort and in minimum time. NDLI provides user group-specific services such as Examination Preparatory for School and College students and job aspirants. Services for Researchers and general learners are also provided. NDLI is designed to hold content of any language and provides interface support for 10 most widely used Indian languages. It is built to provide support for all academic levels including researchers and life-long learners, all disciplines, all popular forms of access devices and differently-abled learners. It is designed to enable people to learn and prepare from best practices from all over the world and to facilitate researchers to perform inter-linked exploration from multiple sources. It is developed, operated and maintained from Indian Institute of Technology Kharagpur.
Learn more about this project from here.
NDLI is a conglomeration of freely available or institutionally contributed or donated or publisher managed contents. Almost all these contents are hosted and accessed from respective sources. The responsibility for authenticity, relevance, completeness, accuracy, reliability and suitability of these contents rests with the respective organization and NDLI has no responsibility or liability for these. Every effort is made to keep the NDLI portal up and running smoothly unless there are some unavoidable technical issues.
Ministry of Education, through its National Mission on Education through Information and Communication Technology (NMEICT), has sponsored and funded the National Digital Library of India (NDLI) project.
| Sl. | Authority | Responsibilities | Communication Details |
|---|---|---|---|
| 1 | Ministry of Education (GoI), Department of Higher Education |
Sanctioning Authority | https://www.education.gov.in/ict-initiatives |
| 2 | Indian Institute of Technology Kharagpur | Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project | https://www.iitkgp.ac.in |
| 3 | National Digital Library of India Office, Indian Institute of Technology Kharagpur | The administrative and infrastructural headquarters of the project | Dr. B. Sutradhar bsutra@ndl.gov.in |
| 4 | Project PI / Joint PI | Principal Investigator and Joint Principal Investigators of the project |
Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon |
| 5 | Website/Portal (Helpdesk) | Queries regarding NDLI and its services | support@ndl.gov.in |
| 6 | Contents and Copyright Issues | Queries related to content curation and copyright issues | content@ndl.gov.in |
| 7 | National Digital Library of India Club (NDLI Club) | Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach | clubsupport@ndl.gov.in |
| 8 | Digital Preservation Centre (DPC) | Assistance with digitizing and archiving copyright-free printed books | dpc@ndl.gov.in |
| 9 | IDR Setup or Support | Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops | idr@ndl.gov.in |
|
Loading...
|