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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Zhong, Nianbing Cen, Yanyan Xin, Xin Liao, Qiang Wu, Ruohua Wang, Zhengkun |
| Description | Country affiliation: China Author Affiliation: Xin X ( Chongqing Key Laboratory of Fiber Optic Sensor and Photodetector, Chongqing Key Laboratory of Modern Photoelectric Detection Technology and Instrument, Chongqing Energy Internet Engineering Center, Chongqing University of Technology, Chongqing 400054, China.); Zhong N ( Chongqing Key Laboratory of Fiber Optic Sensor and Photodetector, Chongqing Key Laboratory of Modern Photoelectric Detection Technology and Instrument, Chongqing Energy Internet Engineering Center, Chongqing University of Technology, Chongqing 400054, China. Electronic address: zhongnianbing@163.com); Liao Q ( Key Laboratory of Low-grade Energy Utilization Technologies and Systems (Chongqing University), Ministry of Education, Chongqing 400030, China. Electronic address: lqzx@cqu.edu.cn.); Cen Y ( Chongqing Key Laboratory of Fiber Optic Sensor and Photodetector, Chongqing Key Laboratory of Modern Photoelectric Detection Technology and Instrument, Chongqing Energy Internet Engineering Center, Chongqing University of Technology, Chongqing 400054, China.); Wu R ( Chongqing Key Laboratory of Fiber Optic Sensor and Photodetector, Chongqing Key Laboratory of Modern Photoelectric Detection Technology and Instrument, Chongqing Energy Internet Engineering Center, Chongqing University of Technology, Chongqing 400054, China.); Wang Z ( Chongqing Key Laboratory of Fiber Optic Sensor and Photodetector, Chongqing Key Laboratory of Modern Photoelectric Detection Technology and Instrument, Chongqing Energy Internet Engineering Center, Chongqing University of Technology, Chongqing 400054, China.) |
| Abstract | We present a novel four-layer structure consisting of bottom, second, third, and surface layers in the sensing region, for a D-shaped step-index fiber-optic evanescent wave (FOEW) sensor. To reduce the background noise, the surface of the longitudinal section in the D-shaped region is coated with a light-absorbing film. We check the morphologies of the second and surface layers, examine the refractive indices (RIs) of the third and surface layers, and analyze the composition of the surface layer. We also investigate the effects of the thicknesses and RIs of the third and surface layers and the LA film on the light transmission and sensitivity of the FOEW sensors. The results highlight the very good sensitivity of the proposed FOEW sensor with a four-layer structure, which reached -0.077 (µg/l) in the detection of the target antibody; the sensitivity of the novel FOEW sensor was 7.60 and 1.52 times better than that of a conventional sensor with a core-cladding structure and an FOEW sensor with a three-layer structure doped with GeO . The applications of this high-sensitivity FOEW sensor can be extended to biodefense, disease diagnosis, and biomedical and biochemical analysis. |
| ISSN | 09565663 |
| Volume Number | 91 |
| e-ISSN | 18734235 |
| Journal | Biosensors and Bioelectronics |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2017-05-15 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Biosensing Techniques Instrumentation Fiber Optic Technology Optical Fibers Polymers Chemistry Animals Antibodies, Anti-idiotypic Analysis Immunology Balsams Drug Combinations Equipment Design Germanium Goats Gutta-percha Immunoglobulin G Mice Zinc Oxide Journal Article Discipline Biotechnology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Nanoscience and Nanotechnology Medicine Biophysics Biomedical Engineering Biotechnology Electrochemistry |
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