NDLI: A stretchable and screen-printed electrochemical sensor for glucose determination in human perspiration.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Canals, A. Abellán-Llobregat, A. Vidal, L. Jeerapan, Itthipon Bandodkar, A. Wang, J. Morallón, E.
Description	Country affiliation: Spain Author Affiliation: Abellán-Llobregat A ( Instituto Universitario de Materiales, Universidad de Alicante, Apartado 99, 03080 Alicante, Spain.); Jeerapan I ( Department of NanoEngineering, University of California, La Jolla, San Diego, CA 92093, USA.); Bandodkar A ( Department of NanoEngineering, University of California, La Jolla, San Diego, CA 92093, USA.); Vidal L ( Departamento de Química Analítica, Nutrición y Bromatología and Instituto Universitario de Materiales, Universidad de Alicante, Apartado 99, 03080 Alicante, Spain.); Canals A ( Departamento de Química Analítica, Nutrición y Bromatología and Instituto Universitario de Materiales, Universidad de Alicante, Apartado 99, 03080 Alicante, Spain.); Wang J ( Department of NanoEngineering, University of California, La Jolla, San Diego, CA 92093, USA.); Morallón E ( Instituto Universitario de Materiales, Universidad de Alicante, Apartado 99, 03080 Alicante, Spain.)
Abstract	Here we present two types of all-printable, highly stretchable, and inexpensive devices based on platinum (Pt)-decorated graphite for glucose determination in physiological fluids. Said devices are: a non-enzymatic sensor and an enzymatic biosensor, the latter showing promising results. Glucose has been quantified by measuring hydrogen peroxide (H O ) reduction by chronoamperometry at -0.35V (vs pseudo-Ag/AgCl) using glucose oxidase immobilized on Pt-decorated graphite. The sensor performs well for the quantification of glucose in phosphate buffer solution (0.25M PBS, pH 7.0), with a linear range between 0 mM and 0.9mM, high sensitivity and selectivity, and a low limit of detection (LOD). Thus, it provides an alternative non-invasive and on-body quantification of glucose levels in human perspiration. This biosensor has been successfully applied on real human perspiration samples and results also show a significant correlation between glucose concentration in perspiration and glucose concentration in blood measured by a commercial glucose meter.
ISSN	09565663
Volume Number	91
e-ISSN	18734235
Journal	Biosensors and Bioelectronics
Language	English
Publisher	Elsevier
Publisher Date	2017-05-15
Publisher Place	Great Britain (UK)
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Biosensing Techniques Instrumentation Electrochemical Techniques Glucose Analysis Sweat Chemistry Adult Elasticity Electrodes Enzymes, Immobilized Equipment Design Female Glucose Oxidase Graphite Humans Hydrogen Peroxide Limit Of Detection Male Platinum Young Adult Evaluation Studies Journal Article Discipline Biotechnology
Content Type	Text
Resource Type	Article
Subject	Nanoscience and Nanotechnology Medicine Biophysics Biomedical Engineering Biotechnology Electrochemistry

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