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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Jelodarian, Zohreh Shokoohinia, Yalda Rashidi, Maryam Ghiasvand, Nastaran Hosseinzadeh, Leila Iranshahi, Mehrdad |
| Description | Country affiliation: Iran Author Affiliation: Jelodarian Z ( a Students research Committee, School of Pharmacy , Kermanshah University of Medical Sciences , Kermanshah , Iran.); Shokoohinia Y ( b Pharmaceutical Sciences Research Center, School of Pharmacy , Kermanshah University of Medical Sciences , Kermanshah , Iran.); Rashidi M ( c Department of Pharmacognosy and Biotechnology, School of Pharmacy , Kermanshah University of Medical Sciences , Kermanshah , Iran.); Ghiasvand N ( a Students research Committee, School of Pharmacy , Kermanshah University of Medical Sciences , Kermanshah , Iran.); Hosseinzadeh L ( b Pharmaceutical Sciences Research Center, School of Pharmacy , Kermanshah University of Medical Sciences , Kermanshah , Iran.); Iranshahi M ( b Pharmaceutical Sciences Research Center, School of Pharmacy , Kermanshah University of Medical Sciences , Kermanshah , Iran.) |
| Abstract | Echinophora cinerea aerial parts are used in folk medicine to cure gastric diseases and as a food seasoning in cheese and yogurt. Besides several pharmacological effects have been assigned to Echinophora spp., there is no phytochemical investigation on this genus other than our previous publication on flavonoids. An acetone extract of E. cinerea afforded three new (1-3) polyacetylenes, one rare monoterpenoid glycoside as verbenone-5-O-ß-D-glycopyranoside (4) and one prenylated coumarin as osthol (5). The structures of all new compounds were elucidated using modern spectroscopic methods, including 2D NMR and mass analyses. The potency of the compounds to induce cell death was determined on SKNMC, PC3 and MCF-7 cell lines using MTT method in which compounds 1 and 2 showed moderate cytotoxic effects, especially against PC3 cells. |
| File Format | HTM / HTML |
| ISSN | 14786419 |
| Journal | Natural Product Research |
| e-ISSN | 14786427 |
| Language | English |
| Publisher | Taylor & Francis |
| Publisher Date | 2017-03-10 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Natural Products |
| Content Type | Text |
| Resource Type | Article |
| Subject | Organic Chemistry Plant Science Analytical Chemistry Biochemistry |
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