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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Wang, Hui Cong, Wen-Li Fu, Ze-Long Chen, Dao-Feng Wang, Qi |
| Description | Author Affiliation: Wang H ( a Key Laboratory of Xinjiang Endemic Phytomedicine Resources Ministry of Education , Shihezi University College of Pharmacy , Shihezi , P.R. China.); Cong WL ( a Key Laboratory of Xinjiang Endemic Phytomedicine Resources Ministry of Education , Shihezi University College of Pharmacy , Shihezi , P.R. China.); Fu ZL ( b Department of Pharmacognosy, School of Pharmacy , Fudan University , Shanghai , P.R. China.); Chen DF ( b Department of Pharmacognosy, School of Pharmacy , Fudan University , Shanghai , P.R. China.); Wang Q ( a Key Laboratory of Xinjiang Endemic Phytomedicine Resources Ministry of Education , Shihezi University College of Pharmacy , Shihezi , P.R. China.) |
| Abstract | Activity-guided fractionation for complement inhibitors led to the isolation of 22 known compounds from Viola kunawarensis. Chemical types include six sterol compounds, three coumarin compounds, five megastigmane compounds, two triterpenoid compounds, two phenylpropanoid compounds, one chlorophyll, one amide, and two lipid compounds. Among which, two sterols (stigmasta-4-ene-3ß,6ß-diol and saringosterone), one amide (aurantiamide acetate) and a norsesquiterpenoid (solalyratin B) exhibited better anti-complementary effects with CH values ranging from 0.02 to 0.08 mM, which are plausible candidates for developing potent anti-complementary agents. |
| File Format | HTM / HTML |
| ISSN | 14786419 |
| Journal | Natural Product Research |
| e-ISSN | 14786427 |
| Language | English |
| Publisher | Taylor & Francis |
| Publisher Date | 2017-03-03 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Natural Products |
| Content Type | Text |
| Resource Type | Article |
| Subject | Organic Chemistry Plant Science Analytical Chemistry Biochemistry |
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