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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Carrieri, Raffaele Manco, Rosanna Sapio, Daniela Iannaccone, Marco Fulgione, Andrea Papaianni, Marina de Falco, Bruna Grauso, Laura Tarantino, Paola Ianniello, Flora Lanzotti, Virginia Lahoz, Ernesto Capparelli, Rosanna |
| Description | Country affiliation: Italy Author Affiliation: Carrieri R ( a Dipartimento di Colture Industriali , Consiglio per la Ricerca in Agricoltura e l'Analisi dell'Economia Agraria (CREA) , Caserta , Italy.); Manco R ( b Dipartimento di Agraria , University of Naples Federico II , Portici, Napoli , Italy.); Sapio D ( b Dipartimento di Agraria , University of Naples Federico II , Portici, Napoli , Italy.); Iannaccone M ( b Dipartimento di Agraria , University of Naples Federico II , Portici, Napoli , Italy.); Fulgione A ( b Dipartimento di Agraria , University of Naples Federico II , Portici, Napoli , Italy.); Papaianni M ( b Dipartimento di Agraria , University of Naples Federico II , Portici, Napoli , Italy.); de Falco B ( b Dipartimento di Agraria , University of Naples Federico II , Portici, Napoli , Italy.); Grauso L ( c Stazione Zoologica 'Anton Dohrn' , Villa Comunale, Napoli , Italy.); Tarantino P ( a Dipartimento di Colture Industriali , Consiglio per la Ricerca in Agricoltura e l'Analisi dell'Economia Agraria (CREA) , Caserta , Italy.); Ianniello F ( b Dipartimento di Agraria , University of Naples Federico II , Portici, Napoli , Italy.); Lanzotti V ( b Dipartimento di Agraria , University of Naples Federico II , Portici, Napoli , Italy.); Lahoz E ( a Dipartimento di Colture Industriali , Consiglio per la Ricerca in Agricoltura e l'Analisi dell'Economia Agraria (CREA) , Caserta , Italy.); Capparelli R ( b Dipartimento di Agraria , University of Naples Federico II , Portici, Napoli , Italy.) |
| Abstract | Mushrooms produce a wide range of bioactive polysaccharides, different from each other in chemical structure and biological effects. In the last years, the idea to develop functional foods or drugs containing fungal polysaccharides is attracting great attention. Fruiting bodies of Basidiomycetes Ganoderma lucidum are commonly used in Oriental medicine to treat several disorders. G. lucidum polysaccharides - mainly ß-glucans and heteroglycans - have numerous biological properties such as antitumour and immunomodulatory activities. This report shows, by gene expression analyses and bioenergetic assays, immunomodulatory properties and capacity to improve glucose metabolism of a water-soluble heteroglycan extracted from mycelium of an Italian isolate of G. lucidum. The findings suggest the use of the heteroglycan as probiotic or ingredient in functional foods, being easy to produce and disperse in a food matrix thanks to its water-solubility. Heteroglycan could exert protective effects in pro-inflammatory conditions and benefits for people characterised by suppressed immune response. |
| File Format | HTM / HTML |
| ISSN | 14786419 |
| Journal | Natural Product Research |
| e-ISSN | 14786427 |
| Language | English |
| Publisher | Taylor & Francis |
| Publisher Date | 2017-01-20 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Natural Products |
| Content Type | Text |
| Resource Type | Article |
| Subject | Organic Chemistry Plant Science Analytical Chemistry Biochemistry |
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