NDLI: Analytical design and fabrication of thermal latch valve driven flexible microscaffold for applications in tissue engineering

Content Provider	IEEE Xplore Digital Library
Author	Chumtong, P. Kojima, M. Horade, M. Ohara, K. Kamiyama, K. Mae, Y. Akiyama, Y. Yamato, M. Arai, T.
Copyright Year	2014
Description	Author affiliation: Grad. Sch. of Eng. Sci., Osaka Univ., Toyonaka, Japan (Chumtong, P.; Kojima, M.; Horade, M.; Kamiyama, K.; Mae, Y.; Arai, T.) \|\| Fac. of Sci. & Technol., Meijo Univ., Nagoya, Japan (Ohara, K.) \|\| Inst. of Adv. Biomed. Eng. & Sci. at TWIns, Tokyo Women's Med. Univ., Tokyo, Japan (Akiyama, Y.; Yamato, M.)
Abstract	This paper presents a flexible microscaffold driven by a thermal latch valve, which helps meet the necessity of engineered tissues with different structures for engineered organ assembly. Unlike the conventional approach, which normally utilizes a fixed scaffold, our flexible microscaffold offers many temporary scaffolds as needed. It consists of a 3×3 microactuator array with a diameter of 500 μm and a pitch of 650 μm. The type of PDMS membrane actuator is designed so as to prevent the leakage of culture media, and have high actuator displacement. The integration of a thermal latch valve with our microscaffold is proposed, as phase-change property of paraffin is beneficial for maintaining the actuator shape over the tissue cultivation period, without energy consumption. The liquid phase of paraffin acts as a valve that allows the adjustment of the actuator shape, while the solid phase acts as a latch that keeps the actuator shape stable over time. The phase-change of paraffin is induced by the joule heat generated by a microheater, made of nickel. The temperature coefficient of resistance and the heating-cooling response of three microheater designs are examined. Experiment results of all designs show that it normally takes 2 minutes to reach over the paraffin's melting point, and 3-4 minutes to cool the heaters down. The high pressure of about 19 kPa is needed in order to obtain an actuator displacement of about 180 μm, which suggests the possibility of using the thermal latch valve to control the scaffold structure.
Starting Page	411
Ending Page	416
File Size	1881774
Page Count	6
File Format	PDF
ISBN	9781479947263
DOI	10.1109/NEMS.2014.6908839
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2014-04-13
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Actuators Valves Latches Fabrication Heating Biological systems Temperature sensors
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

An active microscaffold for applications in tissue engineering

A Silicon Microvalve With Integrated Flow Sensor

Biopolymer deposition for freeform fabrication of tissue engineered scaffolds

Thermal Force Microscopy Of Spin-Valve AMR Sensors

A high power high temperature mechatronic actuator for the electromagnetic valve drive

Freeform fabrication of bioactive tissue scaffolds

Design and fabrication of micro heat flux sensor

Fault detection and diagnosis of valve actuators in HVAC systems

Programmable control of heating for systems with long time delays

Analytical design and fabrication of thermal latch valve driven flexible microscaffold for applications in tissue engineering

Similar Documents

An active microscaffold for applications in tissue engineering

A Silicon Microvalve With Integrated Flow Sensor

Biopolymer deposition for freeform fabrication of tissue engineered scaffolds

Thermal Force Microscopy Of Spin-Valve AMR Sensors

A high power high temperature mechatronic actuator for the electromagnetic valve drive

Freeform fabrication of bioactive tissue scaffolds

Design and fabrication of micro heat flux sensor

Fault detection and diagnosis of valve actuators in HVAC systems

Programmable control of heating for systems with long time delays

Analytical design and fabrication of thermal latch valve driven flexible microscaffold for applications in tissue engineering