NDLI: Optimal control of an inflammatory immune response model

Content Provider	IEEE Xplore Digital Library
Author	Bara, Ouassim Day, Judy Djouadi, Seddik M.
Copyright Year	2015
Description	Author affiliation: Department of Mathematics, University of Tennessee at knoxville, United States (Day, Judy) \|\| Department of Electrical Engineering and Computer Science, University of Tennessee at knoxville, United States (Bara, Ouassim) \|\| Department of Electrical Engineering and computer science, University of Tennessee at Knoxville, United States (Djouadi, Seddik M.)
Abstract	A reduced model of an acute inflammatory response to severe infection is considered. Regulation of the inflammatory response is crucial for restoring the patient to a healthy state. Therefore, an optimal control strategy given by a pro-inflammatory and anti-inflammatory drug treatment are derived. A study of controllability is also presented and the existence result is established. The optimality system composed of four differential equation and their corresponding adjoint equations are solved numerically. Simulation results are presented and different drug treatment strategies are discussed.
Starting Page	1283
Ending Page	1288
File Size	519429
Page Count	6
File Format	PDF
e-ISBN	9781479978861
DOI	10.1109/CDC.2015.7402388
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2015-12-15
Publisher Place	Japan
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Mathematical model Controllability Optimal control Immune system Medical treatment Pathogens Analytical models Ordinary differential equation system Immunology model
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
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