NDLI: Tissue-on-tissue lubricity studies of saliva substitutes as-supplied, mixed with and compared with human saliva from control and xerostomia patients

Content Provider	IEEE Xplore Digital Library
Author	Ganesh, R. Baier, R. Meyer, A.
Copyright Year	2010
Description	Author affiliation: University at Buffalo 110 Parker Hall Buffalo, NY 14214 (Ganesh, R.; Baier, R.; Meyer, A.)
Abstract	Saliva is one of the most complex and important body fluids [1]. It protects and lubricates oral tissues, provides buffering action and antibacterial activity, helps in maintenance of tooth integrity, and aids in taste perception and digestion [2]. The presence of saliva usually is taken for granted. Nevertheless, its diminution or absence can cause painful tongue and mucosa, problems with taste, swallowing, chewing, and phonation, tooth decay and increased risk for infection [3]. Xerostomia, commonly known as “dry mouth”, is a condition caused by diminished salivary flow seen primarily in the elderly experiencing side effects from xerostomic drugs, multi-drug interactions, and cancer therapies. About 30% of the population reports some degree of dry mouth [4], which indicates that it is not an infrequent complaint or patient concern. Management of xerostomia includes maintenance of good oral hygiene, strict adherence to noncariogenic diet and application of topical fluorides [5]. The common clinical approach for these patients is to administer a saliva substitute which functions by moistening the oral cavity to relieve the discomfort caused by oral dryness. The market is flooded with a variety of dry mouth products each claiming to be better than the other. In this study, I have attempted to identify the ingredients of 19 of the saliva substitutes available in the market in order to compare them and see how each ingredient contributes to the efficacy of the product. Unstimulated human saliva may differ in composition and lubricating properties between normal and xerostomic patients and thus their behavior with the saliva substitute admixture. This investigation applied a new tissue-on-tissue lubricity test procedure [6,7], which has shown clinical correlations leading to successful formulations for relieving “dry eye” symptoms, to commercial saliva substitutes as-formulated and after admixture with pre-applied aliquots of unstimulated saliva.
Starting Page	1
Ending Page	2
File Size	196661
Page Count	2
File Format	PDF
ISBN	9781424468799
e-ISBN	9781424469246
DOI	10.1109/NEBC.2010.5458239
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2010-03-26
Publisher Place	USA
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Humans Mouth Testing Pharmaceuticals Spraying Friction Teeth Spectroscopy Strips Protection
Content Type	Text
Resource Type	Article

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Evaluation of wetting ability of five new saliva substitutes on heatpolymerized acrylic resin for retention of complete dentures in dry mouth patients: a comparative study

Xerostomia: Few dry facts about dry mouth

Salivary stimulatory effect of novel low level transcutaneous electro neurostimulator in geriatric patients with xerostomia.

A case-control study to evaluate salivary cortisol levels in patients with dry mouth

Aloe vera for Dry Mouth Denture Patients – Palliative Therapy

Clinical and biochemical evaluation of the saliva of patients with xerostomia induced by radiotherapy

In-mouth mechanism leading to the perception of fat in humans: from detection to preferences. The particular role of saliva

Diagnosis and management of xerostomia and hyposalivation

Salivary levels of cortisol and chromogranin A in patients with dry mouth compared with age-matched controls.

Tissue-on-tissue lubricity studies of saliva substitutes as-supplied, mixed with and compared with human saliva from control and xerostomia patients

Similar Documents

Evaluation of wetting ability of five new saliva substitutes on heatpolymerized acrylic resin for retention of complete dentures in dry mouth patients: a comparative study

Xerostomia: Few dry facts about dry mouth

Salivary stimulatory effect of novel low level transcutaneous electro neurostimulator in geriatric patients with xerostomia.

A case-control study to evaluate salivary cortisol levels in patients with dry mouth

Aloe vera for Dry Mouth Denture Patients – Palliative Therapy

Clinical and biochemical evaluation of the saliva of patients with xerostomia induced by radiotherapy

In-mouth mechanism leading to the perception of fat in humans: from detection to preferences. The particular role of saliva

Diagnosis and management of xerostomia and hyposalivation

Salivary levels of cortisol and chromogranin A in patients with dry mouth compared with age-matched controls.

Tissue-on-tissue lubricity studies of saliva substitutes as-supplied, mixed with and compared with human saliva from control and xerostomia patients