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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Wang, H. L. Lai, L. H. Zhao, J. F. Shang, X. Y. Dong, P. S. Zhu, J. H. Xing, S. Y. |
| Description | Country affiliation: China Author Affiliation: Xing SY ( Department of Cardiology,The First Affiliated Hospital of Henan Science and Technology University, Luoyang, China.); Wang HL ( Department of Cardiology,The First Affiliated Hospital of Henan Science and Technology University, Luoyang, China.); Dong PS ( Department of Cardiology,The First Affiliated Hospital of Henan Science and Technology University, Luoyang, China pingshuandong@126.com.); Lai LH ( Department of Cardiology,The First Affiliated Hospital of Henan Science and Technology University, Luoyang, China.); Zhu JH ( Department of Cardiology,The First Affiliated Hospital of Henan Science and Technology University, Luoyang, China.); Zhao JF ( Department of Cardiology,The First Affiliated Hospital of Henan Science and Technology University, Luoyang, China.); Shang XY ( Department of Cardiology,The First Affiliated Hospital of Henan Science and Technology University, Luoyang, China.) |
| Abstract | The aim of this study was to observe levels of blood brain natriuretic peptides (BNPs) in patients with persistent atrial fibril-lation (AF) before and after catheter ablation. Thirty-six patients with persistent AF (28 successful surgeries and eight recurrent cases) and 36 healthy controls with normal sinus rhythm were recruited for this study. BNP levels in the AF and control groups were measured before and after catheter ablation. BNP levels before surgery were significantly higher in the persistent AF group than in the control group (P < 0.01). The successful surgery group had distinctly lower BNP levels before ablation than the recurrent group (P < 0.01). In the recurrent group, BNP levels 2 h after ablation were significantly lower than those be-fore ablation (P < 0.01); these levels increased after AF recurrence (P < 0.01) and were comparable with those before ablation (P < 0.01). Logistic regression analysis indicated that the BNP level was an inde-pendent factor for and predictor of AF recurrence (P < 0.01). The BNP level in patients with persistent AF is clinically important in predicting and evaluating AF recurrence after ablation. |
| e-ISSN | 16765680 |
| Journal | Genetics and Molecular Research |
| Issue Number | 2 |
| Volume Number | 14 |
| Language | English |
| Publisher | Fundação de Pesquisas Científicas de Ribeirão Preto |
| Publisher Date | 2015-06-26 |
| Publisher Place | Brazil |
| Access Restriction | Open |
| Subject Keyword | Atrial Fibrillation Blood Catheter Ablation Heart Atria Metabolism Natriuretic Peptide, Brain Physiopathology Surgery Biological Markers Case-control Studies Gene Expression Logistic Models Genetics Recurrence Discipline Genetics Discipline Molecular Biology Discipline Bioinformatics |
| Content Type | Text |
| Resource Type | Article |
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