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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Domingues, Joana Parra, Joana Sargento-freitas, João Santana, Isabel |
| Description | Author Affiliation: Parra J ( Department of Neurology, Coimbra Universitary and Hospital Centre, Coimbra, Portugal.) |
| Abstract | A 56-year-old man presented with weight loss, articular pain and minor neurological symptoms progressing over 1 month. Neurosonological evaluation suggested occlusion in intracranial segments of the left vertebral artery (VA) and of both internal carotid arteries (ICA) and hypoechoic halo sign in both superficial temporal arteries. The diagnosis of giant cell arteritis was supported by inflammatory markers and confirmed by biopsy. Despite early steroid initiation, he manifested fluctuant vascular deficits and became lethargic. Brain MRI indicated watershed infarcts and intracranial dissections of left VA and both ICA. The patient was stabilised with the association of prednisolone 2 mg/kg, methotrexate and oral anticoagulation. Since then he has been neurologically asymptomatic and control imaging showed only residual intracranial left VA stenosis, with no signs of temporal artery inflammation or new vascular lesions. This is to the best of our knowledge, the first reported clinical case with such an extensive intracranial involvement with multiple dissections. |
| e-ISSN | 1757790X |
| Journal | BMJ Case Reports |
| Volume Number | 2014 |
| Language | English |
| Publisher | BMJ Publishing Group Ltd. |
| Publisher Place | Great Britain (UK) |
| Access Restriction | Open |
| Subject Keyword | Aneurysm, Dissecting Diagnosis Carotid Artery, Internal Giant Cell Arteritis Intracranial Aneurysm Temporal Arteries Vertebral Artery Etiology Anti-Inflammatory Agents Therapeutic Use Cerebral Angiography Complications Drug Therapy Magnetic Resonance Angiography Magnetic Resonance Imaging Prednisolone Pathology Ultrasonography, Doppler, Transcranial Multidisciplinary |
| Content Type | Text |
| Resource Type | Article |
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