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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Poreba, Rafal Gac, Pawel Poreba, Malgorzata Mazur, Grzegorz |
| Description | Country affiliation: Poland Author Affiliation: Poreba R ( Department of Internal Medicine, Occupational Diseases and Hypertension, Wroclaw Medical University, Borowska 213, PL 50-556 Wroclaw, Poland. sogood@poczta.onet.pl) |
| Abstract | PURPOSE: The aim of the study was to evaluate echocardiographic changes in workers occupationally exposed to low doses of lead. METHODS: We enrolled 63 men occupationally exposed to lead into the study (group I). Unexposed group consisted of 49 healthy men (group II). Blood lead concentration (Pb-B) and blood zinc protoporphyrin concentration (ZnPP) were determined. Transthoracic echocardiographic examination was performed. RESULTS: In the studied groups, selected on the criterion of occupational exposure to lead, comparative analysis of echocardiographic parameters indicated statistically significant differences. A negative linear correlations between ZnPP and E' was observed in group I. It was proved that a higher concentration of ZnPP is independent risk factor of lowering the E' mean value in group I. CONCLUSIONS: Occupational exposure to low doses of lead is associated with the occurrence of discreet morphological and functional heart changes that in the future may predispose to disclosed pathology of heart. |
| File Format | HTM / HTML |
| ISSN | 13826689 |
| Issue Number | 2 |
| Volume Number | 36 |
| e-ISSN | 18727077 |
| Journal | Environmental Toxicology and Pharmacology |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2013-09-01 |
| Publisher Place | Netherlands |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Environmental Health Discipline Pharmacology Echocardiography, Doppler Environmental Pollutants Adverse Effects Heart Diseases Lead Occupational Diseases Occupational Exposure Adult Asymptomatic Diseases Biological Markers Blood Case-control Studies Chi-square Distribution Echocardiography, Doppler, Pulsed Chemically Induced Humans Linear Models Male Middle Aged Multivariate Analysis Occupational Health Predictive Value Of Tests Protoporphyrins Risk Assessment Risk Factors Journal Article Research Support, Non-u.s. Gov't |
| Content Type | Text |
| Resource Type | Article |
| Subject | Health, Toxicology and Mutagenesis Medicine Toxicology Pharmacology |
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