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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Zhang, Ci-Hai Yu, Yue Liang, Yi-Zeng Chen, Xiao-Qing |
| Description | Country affiliation: China Author Affiliation: Zhang CH ( College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, China.); Yu Y ( College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, China.); Liang YZ ( College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, China. Electronic address: yizeng_liang@263.net.); Chen XQ ( College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, China.) |
| Abstract | Glycyrrhiza uralensis, an important Chinese medicine, has a long history of use in China. In this study, three water-soluble polysaccharides fractions (GUPs-1, GUPs-2 and GUPs-3) were isolated and purified from the root of G. uralensis by DEAE-52 and Sephadex G-100 column chromatography. Physicochemical properties and antioxidant activities of the three purified polysaccharides were investigated. The molecular weights of GUPs-1, GUPs-2 and GUPs-3 were 10,160, 11,680 and 13,360 Da, and the ratios of glucose were 23.4%, 14% and 1.13%, respectively. The antioxidant activities of the three purified polysaccharides followed the order: GUPs-1>GUPs-2>GUPs-3. GUPs with lower molecular weight and higher ratio of glucose, basically exhibited higher antioxidant activities at the same concentration. This indicated that the molecular weight and the ratio of monosaccharide composition of the GUPs could affect the antioxidant activities. |
| File Format | HTM / HTML |
| ISSN | 01418130 |
| Volume Number | 79 |
| e-ISSN | 18790003 |
| Journal | International Journal of Biological Macromolecules |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2015-08-01 |
| Publisher Place | Netherlands |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Biochemistry Antioxidants Chemistry Glycyrrhiza Uralensis Iron Chelating Agents Plant Roots Polysaccharides Isolation & Purification Biphenyl Compounds Antagonists & Inhibitors Chromatography, Gel Chromatography, Ion Exchange Glucose Analysis Hydroxyl Radical Molecular Weight Oxidation-reduction Picrates Journal Article Research Support, Non-u.s. Gov't |
| Content Type | Text |
| Resource Type | Article |
| Subject | Structural Biology Molecular Biology Biochemistry |
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