NDLI: Site-specific plaque pH before and after short-term use of 1.5% Arginine dentifrice in caries-free and caries-active individuals

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Site-specific plaque pH before and after short-term use of 1.5% Arginine dentifrice in caries-free and caries-active individuals

Content Provider	Taylor & Francis Online
Author	Carlén, A. Hassan, H. Ghali, L. Wildeboer, D. Lingström, P. Sarwar, S.
Abstract	Objective: To examine the pH response to an acidic challenge in site-specific plaque following a six-week period of using toothpaste consisting of 1.5% arginine and 1450 ppm fluoride or just using 1450 ppm fluoride toothpaste alone, in relation to caries.Methods: Thirty-three healthy adults with no caries (caries-free) or ≥1 current manifest lesion (caries) participated in the study. Interproximal plaque-pH was measured in four sites. Two-weeks after professional cleaning, pH-measurements were performed before and up to 15-min after a 1-min rinse with 10 ml of a 10% sucrose solution. This procedure was repeated after a 6-week test period of using randomly selected toothpaste with 1.5% arginine and fluoride or with fluoride alone. The stimulated salivary flow rate was determined and the salivary-pH and buffer capacity was measured.Results: In the caries group, the use of toothpaste with arginine and fluoride resulted in increased pH-values in the four sites tested. Although it was not statistically significant, increased pH-values were found in the caries-free group. In addition, the whole saliva buffer capacity and pH was increased in the caries group.Conclusion: The most pronounced effect on plaque-pH and stimulated saliva after using arginine and fluoride toothpaste was seen in the caries group.
File Format	PDF HTM / HTML
ISSN	20002297
DOI	10.1080/20002297.2017.1325255
Journal	Journal of Oral Microbiology
Volume Number	9
Issue Number	sup1
Language	English
Publisher	Taylor & Francis
Publisher Date	2017-06-09
Access Restriction	Open
Content Type	Text
Subject	Microbiology (medical) Dentistry Infectious Diseases 3500/3501

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