NDLI: Under rolling loads preliminary research on solute transport in articular cartilage

Content Provider	IEEE Xplore Digital Library
Author	Dan Zhao Chunqiu Zhang Zhenmin Fan Junxia Gao Liping Jin Kexue Jiang
Copyright Year	2010
Description	Author affiliation: School of Mechanical Engineering, Tianjin University of Technology, Tianjin Key Laboratory for Control Theory & Applications in Complicated Industry Systems, China (Dan Zhao; Chunqiu Zhang; Zhenmin Fan; Junxia Gao; Liping Jin; Kexue Jiang)
Abstract	The solute transport in vivo is an important biological behavior within the avascular extracellular matrix of articular cartilage. Mechanical condition drives the cartilage to obtain nutrition and exclude waste during daily activities. The investigation of the transport behavior within the tissue is important to the understanding of the mechanisms of nutritional transport and mechanosignal transduction in cartilage. Under rolling loads, the solute transport within articular cartilage was preliminarily researched using the fluorescence detector to observe solute transport. In experiments, the compression rate of rolling loading is about 20%, rolling speed is 10cm / s, with experimental time respectively are 50s, 100s, and 5 min. Compared with the control group, the results show that the rolling load promoted the solute transport within articular cartilage. Although the exact promotion mechanism is unclear, the rolling loading may provide a potential load to enhance the solute transport, and may be applied to cartilage tissue engineering.
Starting Page	1624
Ending Page	1626
File Size	459222
Page Count	3
File Format	PDF
ISBN	9781424464951
e-ISBN	9781424464982
DOI	10.1109/BMEI.2010.5639584
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2010-10-16
Publisher Place	China
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Knee Training articular cartilage rolling loading Microscopy Loading Fluorescence solute transport device Surface treatment
Content Type	Text
Resource Type	Article

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