NDLI: Temporal and spatial monitoring of temperature-related tissue changes using focused ultrasound phased arrays

Content Provider	IEEE Xplore Digital Library
Author	Konofagou, E.E. Sokka, S. Thierman, J. Hynynen, K.
Copyright Year	2002
Description	Author affiliation: Dept. of Radiol., Boston Univ., MA, USA (Konofagou, E.E.; Sokka, S.; Thierman, J.; Hynynen, K.)
Abstract	Temperature monitoring is most important during the application of thermal treatment, such as in the case of Focused Ultrasound Surgery (FUS). Currently, Magnetic Resonance Imaging (MRI) is the predominant method for temperature mapping of FUS. However, its high cost, low temporal resolution and limited availability and applicability often result in its restricted use. In this paper, a new device for temperature mapping is introduced that only uses focused ultrasound to both apply and monitor the treatment temporally and spatially. By utilizing the principle of the recently introduced Ultrasound-Stimulated Acoustic Emission (USAE) as well as the phased array capability of steering the beam, the temperature distribution at various instants during the application of the treatment could be assessed. The target used here was a silicone gel with tissue-mimicking properties. The temperature spot could be detected during the application of the treatment and the temperature elevation could be both mapped spatially and monitored temporally. In conclusion, an all ultrasound-based system could serve as a more applicable alternative to MR techniques for thermal therapy monitoring. Our plan is to use the same array for the therapy sonication and monitoring of the treatment in the focal zone. This could provide a potential for realizing the ultimate clinical goal: an economic, fully integrated closed loop feedback system for therapy control.
Sponsorship	Ultransonics Ferroelectr., & Frequency Control Soc
Starting Page	1361
Ending Page	1364
File Size	338936
Page Count	4
File Format	PDF
ISBN	0780375823
ISSN	10510117
DOI	10.1109/ULTSYM.2002.1192548
Language	English
Publisher	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Publisher Date	2002-10-08
Publisher Place	Germany
Access Restriction	Subscribed
Rights Holder	Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subject Keyword	Phased arrays Temperature measurement Temperature sensors Monitoring Ultrasonic imaging Focusing Medical treatment Magnetic resonance imaging Surgery Costs
Content Type	Text
Resource Type	Article

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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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